Results 111 to 120 of about 2,510,192 (261)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Synthesis and Biological Profile of Substituted Azetidinyl Carbox­amides, A Novel Class of Herbicidal Acyl-ACP Thioesterase Inhibitors

SynOpen
Guido Bojack, David M. Barber, Luke R. Churchman, Christine Dörnbrack, Stephanie Lee, China M. Payne, Luka Posa, Anna M. Reingruber, Dirk Schmutzler, Jens Frackenpohl   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identifying subgroups of individuals undergoing metabolic bariatric surgery based on behavioral and psychosocial factors: A latent profile analysis. [PDF]

PLoS One
Kuipers EAM, Timmerman JG, van Det MJ, Vermeer M, Vollenbroek-Hutten MMR.   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Adolescents' self-recognition of their facial profile: associations with wellbeing, self-esteem and sociodemographic factors. [PDF]

Dental Press J Orthod
Machado-Silva CB, Paiva SM, Bittencourt JM, Neves LS, Bendo CB.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Development of intraoperative fluoroscopic protocols to avoid rotational malalignment during nailing of femoral fractures: a step-by-step guideline using the lesser trochanter profile or true lateral view. [PDF]

Eur J Orthop Surg Traumatol
Vermue DJ, Bongers PJ, Ten Duis K, Doornberg JN, Jaarsma RL, El Moumni M, Bleeker NJ, Plomp RG, IJpma FFA, 3D Surgery Consortium..   +9 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Profiles/Profils

The Forestry Chronicle, 2000
openaire   +2 more sources