Results 131 to 140 of about 6,148,103 (286)

Symptom profiles of community cases infected by Influenza, RSV, rhinovirus, seasonal coronavirus, and SARS-CoV-2 variants of concern [PDF]

, 2022
Cyril Geismar, Vincent Nguyen, Ellen Fragaszy, Madhumita Shrotri, Annalan M D Navaratnam, Sarah Beale, Thomas Byrne, Wing Lam Erica Fong, Alexei Yavlinsky, Jana Kovar, Susan Hoskins, Isobel Braithwaite, Robert W Aldridge, Andrew Hayward   +13 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

, 2016
Maeghan O’Neill, Cristina Ballesteros, Lucienne Tritten, Erica Burkman, Weam I. Zaky, Jianguo Xia, Andrew R. Moorhead, Steven A. Williams, Timothy G. Geary   +8 more
openalex   +1 more source

PEOPLE AND ORGANIZATIONAL CULTURE: A PROFILE COMPARISON APPROACH TO ASSESSING PERSON-ORGANIZATION FIT

, 1991
C. O'Reilly, Jennifer A. Chatman, D. Caldwell   +2 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Study of the effect of synthesis temperature and thermal aging on structural, dielectric properties and phase composition in NiO/NiAl2O4 composite ceramics

Materials Research Express
In modern materials science, a considerable amount of research is focused on obtaining new ceramic materials to create efficient functional elements. Acquiring highly efficient and stable ceramic catalysts for alternative energy is an important task that
Rafael I Shakirzyanov, Daryn B Borgekov, Yuriy A Garanin, Artem L Kozlovskiy, Natalia O Volodina, Dmitriy I Shlimas, Maxim V Zdorovets   +6 more
doaj   +1 more source

Cytokine profiles during experimental Chagas' disease [PDF]

, 1998
Maria José F. Morato, Daniel G. Colley, Malcolm R. Powell   +2 more
openalex   +1 more source

Bibliometric Profile and Density Visualizing Analysis of Yoga Intervention in Type 2 Diabetes

, 2021
Ramya Ramamoorthi, Daniel Gahreman, Timothy Skinner, Simon Moss   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source