Results 31 to 40 of about 10,838,787 (366)
eLife, 2021 High-throughput single-cell methods have uncovered substantial heterogeneity in the pool of hematopoietic stem and progenitor cells (HSPCs), but how much instruction is inherited by offspring from their heterogeneous ancestors remains unanswered. Using a
Tamar Tak +8 more
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Age-related inflammation triggers skeletal stem/progenitor cell dysfunction
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance As we age, our capacity for tissue repair and regeneration in response to injury declines. Accordingly, bone repair is delayed and impaired in older patients.
A. M. Josephson +14 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2022 Loss of muscle mass and strength contributes to decreased independence and an increased risk for morbidity and mortality. A better understanding of the cellular and molecular mechanisms underlying muscle atrophy therefore has significant clinical and ...
Emily Parker +12 more
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Circulating endothelial progenitor cells [PDF]
British Journal of Cancer, 2005 Angiogenesis research investigates the formation of new blood vessels in wound healing, tumour growth and embryonic development. Circulating, bone marrow-derived endothelial progenitor cells (EPCs) were first described 8 years ago, yet the exact nature of these endothelial precursor cells remains unclear.
Barbara Garmy-Susini, Judith A. Varner
openaire +3 more sources
Cells, 2013 Tumorigenesis is often described as a result of accumulated mutations that lead to growth advantage and clonal expansion of mutated cells. There is evidence in the literature that cancer cells are influenced by the microenvironment.
Sonia M. Rosenfield, Gilbert H. Smith
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Maintenance of Neural Progenitor Cell Stemness in 3D Hydrogels Requires Matrix Remodeling
Nature Materials, 2017 Neural progenitor cell (NPC) culture within 3D hydrogels is an attractive strategy for expanding a therapeutically-relevant number of stem cells. However, relatively little is known about how 3D material properties such as stiffness and degradability ...
C. Madl +10 more
semanticscholar +1 more source
Joint Development Involves a Continuous Influx of Gdf5-Positive Cells
Cell Reports, 2016 Synovial joints comprise several tissue types, including articular cartilage, the capsule, and ligaments. All of these compartments are commonly assumed to originate from an early set of Gdf5-expressing progenitors populating the interzone domain.
Yulia Shwartz +3 more
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Frontiers in Cell and Developmental Biology, 2022 Adipose tissue (AT) is an endocrine organ with a central role on whole-body energy metabolism and development of metabolic diseases. Single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, respectively) analyses in mice and human AT have ...
Tainara C. Michelotti +11 more
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Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Mesenchymal progenitor cells play important roles in the formation of skeletal tissues; however, how cell fates of mesenchymal progenitor cells are regulated remains largely unclear.
A. Takahashi +11 more
semanticscholar +1 more source
Myocardial Ischemia and Mobilization of Circulating Progenitor Cells
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundThe response of progenitor cells (PCs) to transient myocardial ischemia in patients with coronary artery disease remains unknown. We aimed to investigate the PC response to exercise‐induced myocardial ischemia (ExMI) and compare it to flow ...
Muhammad Hammadah +30 more
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