Results 51 to 60 of about 595,486 (312)

Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues

Journal of Lipid Research, 2013
Brown adipose tissues (BAT) are derived from a myogenic factor 5 (Myf5)-expressing cell lineage and white adipose tissues (WAT) predominantly arise from non-Myf5 lineages, although a subpopulation of adipocytes in some WAT depots can be derived from the ...
Tizhong Shan, Xinrong Liang, Pengpeng Bi, Pengpeng Zhang, Weiyi Liu, Shihuan Kuang   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The Musashi family RNA-binding proteins in stem cells

Biomolecular Concepts, 2010
The Musashi family is an evolutionarily conserved group of RNA-binding proteins. In mammal, two members of the group, Msi1 and Msi2, have been identified to date.
Horisawa Kenichi, Imai Takao, Okano Hideyuki, Yanagawa Hiroshi   +3 more
doaj   +1 more source

A method to investigate radial glia cell behavior using two-photon time-lapse microscopy in an ex vivo model of spinal cord development.

Frontiers in Neuroanatomy, 2014
The mammalian central nervous system (CNS) develops from multipotent progenitor cells, which proliferate and differentiate into the various cell types of the brain and spinal cord.
Janelle M.P. Pakan, Kieran William Mcdermott   +1 more
doaj   +1 more source

Novel role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in adhesion and migration of 32D myeloid progenitor cells [PDF]

, 2012
Rho GTPases are involved in homing and mobilization of hematopoietic stem and progenitor cells due to their impact on cytoskeleton remodeling. We have previously shown that inhibition of Rho, Rac and Cdc42 clearly impairs adhesion of normal and leukemic ...
Aschenbrenner, Frank, Bug, Gesine, Henschler, Reinhard, Hofmann, Wolf-Karsten, Kampfmann, Manuela, Komor, Martina, Ruthardt, Martin, Rüster, Brigitte Inge, Schwarz, Kerstin   +8 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Improving the viability of tissue‐resident stem cells using an organ‐preservation solution

FEBS Open Bio, 2019
Human clinical specimens are a valuable source of tissue‐resident stem cells, but such cells need to be collected immediately after tissue collection. To extend the timescale for collection from fresh human samples, we developed a new extracellular fluid
Takaya Suzuki, Chiharu Ota, Naoya Fujino, Yukiko Tando, Satoshi Suzuki, Mitsuhiro Yamada, Takashi Kondo, Yoshinori Okada, Hiroshi Kubo   +8 more
doaj   +1 more source

Sex Differences in Circulating Progenitor Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundLower levels of circulating progenitor cells (PCs) reflect impaired endogenous regenerative capacity and are associated with aging, vascular disease, and poor outcomes.
Matthew L. Topel, Salim S. Hayek, Yi‐An Ko, Pratik B. Sandesara, Ayman Samman Tahhan, Iraj Hesaroieh, Ernestine Mahar, Greg S. Martin, Edmund K. Waller, Arshed A. Quyyumi   +9 more
doaj   +1 more source

Progenitor-Based Cell Biological Aspects of Neocortex Development and Evolution

Frontiers in Cell and Developmental Biology, 2022
During development, the decision of stem and progenitor cells to switch from proliferation to differentiation is of critical importance for the overall size of an organ. Too early a switch will deplete the stem/progenitor cell pool, and too late a switch
Samir Vaid, Wieland B. Huttner
doaj   +1 more source

Impaired DNA replication within progenitor cell pools promotes leukemogenesis. [PDF]

, 2005
Impaired cell cycle progression can be paradoxically associated with increased rates of malignancies. Using retroviral transduction of bone marrow progenitors followed by transplantation into mice, we demonstrate that inhibition of hematopoietic ...
Ames, Anderson, Andriy Marusyk, Begg, Blagosklonny, Calabretta, Castor, Chang, Choi, Christensen, Christopher C Porter, Christopher Kemp, DeGregori, Dimova, Field, Furgerson, Ganna Bilousova, Gottlieb, Greaves, Hanahan, Hariharan, Jacks, James DeGregori, Jamieson, Just, Kinder, Li, Li, Lightfoot, Lin, Luch, Lundin, Matioli, Milner, Murga, Passegue, Pear, Penit, Pui, Robert D Cardiff, Ryan, Saintigny, Sawyers, Schaefer, Shechter, Sirard, Skibola, Skorski, Spangrude, Sterkers, Van Etten, Wallace-Brodeur, Wong, Wu, Yamasaki, Zhang, Zhu, Zimmerman   +57 more
core   +3 more sources