Results 31 to 40 of about 1,562 (267)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Scientia Agricola, 1995 A cultura de uvas de mesa em São Paulo vem aumentando de importância, o que é flagrante pelos incrementos na área plantada verificados nos últimos anos.
C.P. Ferri, C.V. Pommer
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Revista de Investigaciones Marinas, 2023 Los Laboratorios de Producción de Postlarvas requieren de un aumento del porcentaje de cópulas en reproductores obtenidos en ciclo cerrado, para poder satisfacer la demanda de postlarvas de las granjas camaroneras. En este trabajo se evalúa el desempeño
Lourdes Pérez-Jar +4 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Iatreia, 2016 Introduction: In order to carry out an autologous transplantation, hematopoietic stem cells should be mobilized to peripheral blood and later collected by apheresis.
Combariza, Juan F. +4 more
doaj +1 more source
Revista Española de Pedagogía, 2021 Los progenitores se preguntan en multitud de ocasiones qué y cómo proceder ante las diferentes situaciones surgidas con sus hijos. A estas cuestiones intentan dar respuesta los programas de educación parental (PEP).
Francisco José Rubio Hernández +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
ON THE PROGENITORS OF GALACTIC NOVAE [PDF]
The Astrophysical Journal, 2012 Of the approximately 400 known Galactic classical novae, only ten of them, the recurrent novae, have been seen to erupt more than once. At least eight of these recurrents are known to harbor evolved secondary stars, rather than the main sequence secondaries typical in classical novae.
Darnley, M. J. +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source