EMBO Molecular Medicine, 2019 Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder caused by progerin, a mutant lamin A variant. HGPS patients display accelerated aging and die prematurely, typically from atherosclerosis complications. Recently, we demonstrated that
Magda R Hamczyk +9 more
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Multilevel analysis of nuclear dynamics in lamin perturbed fibroblasts [PDF]
, 2010 The nuclear lamina provides structural support to the nucleus and has a central role in defining nuclear organization. Defects in its filamentous constituents, the lamins, lead to a class of diseases collectively referred to as laminopathies.
Broers, Jos +7 more
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Vascular cells derived from Hutchinson-Gilford progeria syndrome (HGPS) inducible pluripotent stem cells [PDF]
, 2014 To study the vulnerability of smooth muscle cells (SMCs) in Hutchinson-Gilford Progeria Syndrome (HGPS)
Ferreira, Lino +4 more
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Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome [PDF]
, 2022 Xiaojing Mao +7 more
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Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome [PDF]
, 2021 Amanda Sánchez‐López +17 more
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Yawkey Foundations 2010 Grants Report [PDF]
, 2011 Contains mission statement, board chair and president's message; grantee profiles in the areas of health, education, and human services; 2010 grants list and highlights; grant guidelines; and list of board ...
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Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging [PDF]
, 2009 Sofía Rodríguez +3 more
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Congenital entropion with progeria: 4 going 40
Indian Journal of Ophthalmology, 2022 Himika Gupta, Suhas Pawar
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Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress [PDF]
, 2005 Mauro Paradisi +5 more
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