Results 61 to 70 of about 491 (128)
Posttranslational Modifications of Lamin A/C and Cardiac Aging: A Short Review
Journal of the Practice of Cardiovascular SciencesCardiac aging is considered as natural and age-related changes in the heart, which can lead to a decline in heart function. Cardiac aging increases the risk of heart failure, atrial fibrillation, and other cardiovascular complications.
Vikas Tiwari +2 more
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Revista chilena de pediatría, 2002 Resumen La progeria o síndrome de Hutchinson-Gilford esun síndrome poco frecuente. Consiste en la aparición de signos de envejecimiento en niños entre su primer y segundo año de vida. La mayoría de los casos de progeria son esporádicos, lo cual plantea la posibilidad de un patrón de herencia autosómico dominante por mutación de novo.
Pardo V., Rosa Andrea +1 more
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Management of cataract in Werner syndrome
Indian Journal of Ophthalmology, 2018 Werner syndrome (WS) is a rare progressive disorder. It is characterized by the appearance of unusually accelerated aging (progeria) including bilateral senile cataract. Here, we report a successful management of hypermature cataract in WS.
Rakhi Kusumesh +3 more
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Cell Reports, 2018 Summary: Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disease caused by a truncated lamin A protein (progerin) that drives cellular and organismal decline.
Ray Kreienkamp +9 more
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Erythrocyte Senescence in a Model of Rat Displaying Hutchinson-Gilford Progeria Syndrome
Analytical Cellular Pathology, 2018 Background. Increased oxidative stress is a major cause of aging and age-related diseases. Erythrocytes serve as good model for aging studies. Dihydrotachysterol is known to induce premature aging feature in rats mimicking Hutchinson-Gilford progeria ...
Manoj Kumar Chaudhary +1 more
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Current advances and future prospects of cell reprogramming in progeroid syndromes
Frontiers in Cell and Developmental BiologyCell reprogramming consists in the reverse process to cell differentiation, making cells lose their identity and age-related characteristics and granting an increased potential for proliferation and redifferentiation on different lineages.
Lucas Moledo-Nodar +6 more
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International Journal of Medical Students, 2015 Genetic mutations are becoming more deleterious day by day. Mutations of Genes named FBN1, AKT1, LMNA result specific protein malfunction that in turn commonly cause Marfan syndrome, Proteus syndrome, and Progeria, respectively.
Tonmoy Biswas
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Nursing & Healthcare International JournalProgeria is a rare genetic disease with striking features that resemble accelerated aging. The inheritance pattern, paternal age effect, and lack of consanguinity argue that it is due to a sporadic dominant mutation. We have observed elevated levels of hyaluronic acid (HA) excretion in progeria patients.
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Progeria and Atherosclerosis [PDF]
Archives of Disease in Childhood, 1955 A J, KEAY, M F, OLIVER, G S, BOYD
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Medicina U.P.B.Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare and devastating genetic disorder characterized by premature aging. This condition is caused by an autosomal dominant mutation in the LMNA gene, which leads to the production of the defective protein ...
María Elena Arana Baquero +2 more
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