Results 81 to 90 of about 9,936 (203)
Prelamin A degradation pathways and progeria
, 2012 The nuclear lamina plays a key role in cellular senescence. Lamin A precursors have been implicated in the normal ageing process, while mutations in lamin A/C cause progeroid diseases, such as Mandibuloacral dysplasia and Hutchinson-Gilford progeria, or ...
Michela Ortolani +12 more
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Erythrocyte Senescence in a Model of Rat Displaying Hutchinson-Gilford Progeria Syndrome
Analytical Cellular Pathology, 2018 Background. Increased oxidative stress is a major cause of aging and age-related diseases. Erythrocytes serve as good model for aging studies. Dihydrotachysterol is known to induce premature aging feature in rats mimicking Hutchinson-Gilford progeria ...
Manoj Kumar Chaudhary +1 more
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Revista chilena de pediatría, 2002 Resumen La progeria o síndrome de Hutchinson-Gilford esun síndrome poco frecuente. Consiste en la aparición de signos de envejecimiento en niños entre su primer y segundo año de vida. La mayoría de los casos de progeria son esporádicos, lo cual plantea la posibilidad de un patrón de herencia autosómico dominante por mutación de novo.
Pardo V., Rosa Andrea +1 more
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Nuclear Rupture in Progeria Expressing Cells [PDF]
, 2018 Cells regularly take on various types of force in the body. They have structures that are able to mediate, transfer and respond to the forces. A mutation in force regulating proteins such as lamin in the nucleus or the KASH domain which connects the ...
Bathula, Kranthidhar
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, 2018 Hutchinson-Gilford Progeria Syndrome (HGPS) is characterized by the progressive accumulation of progerin, an aberrant form of Lamin A, leading to chromatin structure disruption, in particular by interfering with Lamina Associated Domains.
Endre Sebestyén +8 more
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Hutchinson-Gilford progeria syndrome
, 2010 Progeria is a rare genetic disorder characterized by premature aging, involving the skin, bones, heart, and blood vessels. We report a 4-year-old boy who presented with clinical manifestations of progeria.
Sharad Mehta +7 more
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Progeria and the early aging in children: a case report [PDF]
, 2016 The Hutchinson-Gilford syndrome or progeria is a rare autosomal dominant syndrome characterized by premature aging and involvement of internal systems, such as the circulatory and locomotor.
Celli, Adriane +6 more
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Current advances and future prospects of cell reprogramming in progeroid syndromes
Frontiers in Cell and Developmental BiologyCell reprogramming consists in the reverse process to cell differentiation, making cells lose their identity and age-related characteristics and granting an increased potential for proliferation and redifferentiation on different lineages.
Lucas Moledo-Nodar +6 more
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Progeria and Atherosclerosis [PDF]
Archives of Disease in Childhood, 1955 A J, KEAY, M F, OLIVER, G S, BOYD
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, 2004 Progeria is a rare, genetically determined condition characterized by accelerated aging in children. Its name is derived from Greek (Geron) and means "prematurely old".
Hennekam, Raoul C. M. +11 more
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