Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females. [PDF]
PLoS Pathogens, 2016 Over 100 million women use progesterone therapies worldwide. Despite having immunomodulatory and repair properties, their effects on the outcome of viral diseases outside of the reproductive tract have not been evaluated.
Olivia J Hall +7 more
doaj +2 more sources
Elevated Progesterone Levels on the Day of Oocyte Maturation May Affect Top Quality Embryo IVF Cycles. [PDF]
PLoS ONE, 2016 In contrast to the impact of elevated progesterone on endometrial receptivity, the data on whether increased progesterone levels affects the quality of embryos is still limited. This study retrospectively enrolled 4,236 fresh in vitro fertilization (IVF)
Bo Huang +7 more
doaj +2 more sources
Progesterone Resistance in Endometriosis: Current Evidence and Putative Mechanisms
International Journal of Molecular Sciences, 2023 Endometriosis is an estrogen-dependent disease characterized by the growth of endometrial-like tissue outside the uterus. Progestins are currently the most commonly used treatment for endometriosis because of their excellent therapeutic effects and ...
Ping Zhang, Guoyun Wang
semanticscholar +1 more source
Progesterone Actions and Resistance in Gynecological Disorders
Cells, 2022 Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen and progesterone disrupts their complex regulatory mechanisms, leading to
J. MacLean, Kanako Hayashi
semanticscholar +1 more source
Progesterone: A Steroid with Wide Range of Effects in Physiology as Well as Human Medicine
International Journal of Molecular Sciences, 2022 Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In current reproductive medicine, progesterone and its analogues play crucial roles.
L. Kolátorová +4 more
semanticscholar +1 more source
Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update.
Journal of Clinical Oncology, 2020 PURPOSE To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists estrogen (ER) and progesterone receptor (PgR) testing in breast cancer guideline. METHODS A multidisciplinary international Expert Panel
K. Allison +21 more
semanticscholar +1 more source
Progesterone and breast cancer.
Endocrine reviews, 2020 Synthetic progestogens (progestins) have been linked to increased breast cancer risk; however, the role of endogenous progesterone in breast physiology and carcinogenesis is less clearly defined.
B. Trabert +3 more
semanticscholar +1 more source
Micronized vaginal progesterone to prevent miscarriage: a critical evaluation of randomized evidence
American Journal of Obstetrics and Gynecology, 2020 Progesterone is essential for the maintenance of pregnancy. Several small trials have suggested that progesterone supplementation may reduce the risk of miscarriage in women with recurrent or threatened miscarriage.
A. Coomarasamy +29 more
semanticscholar +1 more source
Progesterone in the Brain: Hormone, Neurosteroid and Neuroprotectant
International Journal of Molecular Sciences, 2020 Progesterone has a broad spectrum of actions in the brain. Among these, the neuroprotective effects are well documented. Progesterone neural effects are mediated by multiple signaling pathways involving binding to specific receptors (intracellular ...
R. Guennoun
semanticscholar +1 more source
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone
Signal Transduction and Targeted Therapy, 2022 Whether and how innate antiviral response is regulated by humoral metabolism remains enigmatic. We show that viral infection induces progesterone via the hypothalamic-pituitary-adrenal axis in mice.
Shan Su +12 more
doaj +1 more source