Results 51 to 60 of about 522,321 (423)

Vaginal progesterone decreases preterm birth ≤ 34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta‐analysis including data from the OPPTIMUM study

Ultrasound in Obstetrics and Gynecology, 2016
To evaluate the efficacy of vaginal progesterone administration for preventing preterm birth and perinatal morbidity and mortality in asymptomatic women with a singleton gestation and a mid‐trimester sonographic cervical length (CL) ≤ 25 mm.
Roberto Romero, K. Nicolaides, A. CONDE-AGUDELO, J. O'Brien, E. Cetingoz, E. Fonseca, G. Creasy, S. Hassan, S. Hassan   +8 more
semanticscholar   +1 more source

Regulation by Progestins, Corticosteroids and RU486 of Activation of Elephant Shark and Human Progesterone Receptors: An Evolutionary Perspec [PDF]

arXiv, 2021
We investigated progestin and corticosteroid activation of the progesterone receptor (PR) from elephant shark (Callorhinchus milii), a cartilaginous fish belonging to the oldest group of jawed vertebrates. Comparison with human PR experiments provides insights into the evolution of steroid activation of human PR.
arxiv  

Fluorescent ligand for human progesterone receptor imaging in live cells. [PDF]

, 2013
We employed molecular modeling to design and then synthesize fluorescent ligands for the human progesterone receptor. Boron dipyrromethene (BODIPY) or tetramethylrhodamine were conjugated to the progesterone receptor antagonist RU486 (Mifepristone ...
Baker, Michael E, Ellies, Lesley G, Friedman, Beth, Kanter, Joan, Tsien, Roger Y, Weinstain, Roy   +5 more
core   +1 more source

Progesterone receptor modulates estrogen receptor-α action in breast cancer

Nature, 2015
Progesterone receptor (PR) expression is used as a biomarker of oestrogen receptor-α (ERα) function and breast cancer prognosis. Here we show that PR is not merely an ERα-induced gene target, but is also an ERα-associated protein that modulates its ...
Hisham Mohammed, I. A. Russell, R. Stark, O. Rueda, Theresa E. Hickey, G. Tarulli, Aurélien A. Sérandour, S. Birrell, A. Bruna, Amel Saadi, S. Menon, J. Hadfield, Michelle Pugh, Ganesh V. Raj, Gordon D. Brown, C. D’Santos, Jessica L. L. Robinson, Grace O. Silva, Rosalind Launchbury, Charles M. Perou, J. Stingl, C. Caldas, W. Tilley, Jason S. Carroll   +23 more
semanticscholar   +1 more source

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the ILAE/AES joint translational TASK force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila, Tore Eid, James D. Mills, Michael S. Hildebrand, Gary P. Brennan, Susan A. Masino, Vicky Whittemore, Piero Perucca, Christopher A. Reid, Manisha Patel, Kevin K. Wang, Erwin A. van Vliet   +11 more
wiley   +1 more source

Divergent Evolution of Progesterone and Mineralocorticoid Receptors in Terrestrial Vertebrates and Fish Influences Endocrine Disruption [PDF]

arXiv, 2021
There is much concern about disruption of endocrine physiology regulated by steroid hormones in humans, other terrestrial vertebrates and fish by industrial chemicals, such as bisphenol A, and pesticides, such as DDT. These endocrine-disrupting chemicals influence steroid-mediated physiology in humans and other vertebrates by competing with steroids ...
arxiv  

Estrogen and progesterone promote breast cancer cell proliferation by inducing cyclin G1 expression

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018
Breast cancer is the most common cause of cancer among women in most countries (WHO). Ovarian hormone disorder is thought to be associated with breast tumorigenesis.
Jintao Tian, B. Ran, C. Zhang, D. Yan, X-H. Li   +4 more
semanticscholar   +1 more source

Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue

Pharmaceutics, 2021
Following oral administration, the bioavailability of progesterone is low and highly variable. As a result, no clinically relevant, natural progesterone oral formulation is available.
Zoe Coombes, Katie Plant, Cristina Freire, Abdul W. Basit, Philip Butler, R. Steven Conlan, Deyarina Gonzalez   +6 more
doaj   +1 more source

Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization [PDF]

, 2011
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright @ 2011 Spandidos Publications Ltd.A vital function of the human placenta is to produce steroid hormones such as ...
Foster, H, Goumenou, A, Karteris, E, Rand-Weaver, M, Thomas, P, Zachariades, E   +5 more
core   +1 more source

Progesterone for premenstrual syndrome [PDF]

Cochrane Database of Systematic Reviews, 2006
Premenstrual Syndrome (PMS) is the term for severe symptoms experienced by about 5% of menstruating women up to two weeks before their menstrual periods, but not at other times. Treatment with progesterone may restore a deficiency, or balance the level of progesterone with other menstrual hormones. Progesterone therapy may reduce the effects of falling
Ford, O., Lethaby, A., Roberts, H., Mol, B.   +3 more
openaire   +5 more sources