Journal of Kerman University of Medical Sciences, 2022 Background: Insufficient serum progesterone level in the implantation phase may reduce the rate of pregnancy during freeze embryo transfer (FET) cycles.
Marzieh Mehrafza
doaj +1 more source
Multi-Kink Quantile Regression for Longitudinal Data with Application to the Progesterone Data Analysis [PDF]
arXiv, 2021 Motivated by investigating the relationship between progesterone and the days in a menstrual cycle in a longitudinal study, we propose a multi-kink quantile regression model for longitudinal data analysis. It relaxes the linearity condition and assumes different regression forms in different regions of the domain of the threshold covariate.
arxiv
Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]
, 2012 Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
A Shennan +37 more
core +4 more sources
The high concentration of progesterone is harmful for endometrial receptivity and decidualization
Scientific Reports, 2018 Progesterone is required for the establishment and maintenance of mammalian pregnancy and widely used for conservative treatment of luteal phase deficiency in clinics.
Yu-Xiang Liang +6 more
semanticscholar +1 more source
Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis [PDF]
Molecular and Cellular Endocrinology, 436:10--22 (2016), 2018 Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric modulators (NAMs) of follicle-stimulating hormone receptor (FSHR), ADX68692 and ADX68693, with differential effects on FSHR-mediated steroidogenesis and ovulation.
arxiv +1 more source
Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]
, 2014 Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou +28 more
core +3 more sources
Molecular evidence of functional progesterone withdrawal in human myometrium
Nature Communications, 2016 Progesterone suppresses uterine contractility acting through its receptors (PRA/B). The mechanism by which human labour is initiated in the presence of elevated circulating progesterone has remained an enigma since Csapo first theorized of a functional ...
Lubna Nadeem +5 more
semanticscholar +1 more source
Aldosterone and Dexamethasone Activate African Lungfish Mineralocorticoid Receptor: Increased Activation After Removal of the Amino-Terminal Domain [PDF]
arXiv, 2021 Aldosterone, the main physiological mineralocorticoid in humans and other terrestrial vertebrates, first appears in lungfish, which are lobe-finned fish that are forerunners of terrestrial vertebrates. Aldosterone activation of the MR regulates internal homeostasis of water, sodium and potassium, which was critical in the conquest of land by ...
arxiv
Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]
, 2016 Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol +6 more
core +2 more sources
Gut Microbes\Levels of progesterone, an endogenous female hormone, increase after ovulation; progesterone is crucial in the luteal phase to maintain successful pregnancy and prevent early miscarriage.
Mei-Jou Chen +15 more
doaj +1 more source