Results 221 to 230 of about 219,338 (264)

Progesterone ”Receptor“ in Rat Ovary*

Endocrinology, 1979
A soluble thermolabile protein with many characteristics of a progesterone receptor has been identified in ovaries of estrogen-stimulated, hypophysectomized, immature female rats. A potent synthetic progestin R5020 (17,21-dimethyl-19-nor-pregna-4, 9-diene-3, 20-dione) and a progestin-receptor complex stabilizer (glycerol) were employed.
Aaron J. W. Hsueh, J. R. Schreiber
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Progesterone antagonists and progesterone receptor modulators: an overview

Steroids, 2003
Since the original description of the structure of the antiprogestin, mifepristone, was published, numerous related compounds have been synthesized which may function as progesterone antagonists (PAs) or progesterone receptor modulators (PRMs). The latter are mixed agonists-antagonists.
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Progesterone receptor antagonists.

Current opinion in investigational drugs (London, England : 2000), 2006
Since the discovery of the progesterone receptor antagonist mifepristone, numerous additional compounds, which display a spectrum of biological actions ranging from full antagonist to those with mixed agonist/antagonist activity, have been synthesized. The latter are referred to as selective progesterone receptor modulators. Long-term administration of
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Oestrogen and progesterone receptors

1979
According to current views, steroid hormones function by binding to specific receptor proteins present in responsive cells. Although a general scheme of steroid interaction with the cell has been elucidated, the precise mechanism by which steroids enhance RNA and protein synthesis is still unknown.
R. J. B. King, P. W. Jungblut, A. M. Kaye, G. A. Puca, H.I. Jacobson   +4 more
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PROGESTERONE RECEPTORS IN BREAST CANCER

Australian and New Zealand Journal of Surgery, 1984
Sixty‐six women who had received hormonal therapy for advanced disease were assessed for objective response to treatment. Another 51 patients who had received chemotherapy were similarly studied. Progesterone receptor was of no value as a predictor of patients unlikely to respond to hormone therapy, though it may have a role in predicting patients ...
Francis J. Morgan, Ronald J. Mercer, George C. Rennie, Tat Hean Lie, Robert M. Bryan, R. C. Bennett   +5 more
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UTERINE PROGESTERONE AFTER PROGESTERONE TREATMENT: ON THE DISAPPEARANCE OF CYTOSOLIC PROGESTERONE RECEPTORS

Journal of Steroid Biochemistry, 1979
Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Structural analyses of progesterone receptors

Journal of Steroid Biochemistry, 1986
Progesterone receptors of T47Dco human breast cancer cells consist of two equimolar hormone-binding proteins of mol. wt approximately 85,000 (A protein) and 115,000 (B protein). Both proteins can be demonstrated in intact cells by in situ photoaffinity labeling; that is, in cells treated with the synthetic progestin [3H]R5020, irradiated 2 min with 300
Lisa L. Wei, Kathryn B. Horwitz, Mary D. Francis   +2 more
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Estrogen and progesterone receptors in meningiomas

Journal of Neurosurgery, 1984
✓ Two-thirds of all meningiomas and four-fifths of intraspinal and sphenoidal meningiomas occur in women. Meningiomas frequently enlarge or become symptomatic during pregnancy or during the luteal phase of the menstrual cycle. There is an increased incidence of meningiomas in women with breast carcinoma. In a series of 23 patients with meningiomas, the
Thomas Dalton, Louis W. Solomon, Michael Salcman, Thomas B. Ducker, David W. Cahill, Nasir Bashirelahi   +5 more
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Progesterone receptors in human endometrium

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1982
Progesterone receptor levels were determined in the cytoplasm obtained from endometrial tissue of 21 patients. In normal women, the levels of progesterone receptors were related to the stage of the menstrual cycle with highest levels occurring in the early secretory stage.
R.N. Kurl, N.M. Borthwick
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Progesterone “Receptor” in Human Endometrium

Endocrinology, 1974
A ligand-specific progesterone-binding protein which migrated in sucrose gradients, as a 4–5S complex, has been identified in endometrial cytosol. The association constant (Ka) for progesterone binding to cytosol protein was estimated at 1.2–3.4 i 109 ...
Willard M. Allen, Walter G. Wiest, B. Ramanath Rao   +2 more
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