The Role of Progesterone Receptors in Breast Cancer. [PDF]
Drug Des Devel Ther, 2022 The progesterone receptor (PR) modulates estrogen receptors α (ERα) action in breast cancer; it is an upregulated target gene of ER, and its expression is dependent on estrogen.
Li Z, Wei H, Li S, Wu P, Mao X.
europepmc +2 more sources
Membrane Progesterone Receptors (mPRs, PAQRs): Review of Structural and Signaling Characteristics. [PDF]
Cells, 2022 The role of membrane progesterone receptors (mPRs), which belong to the progestin and adipoQ receptor (PAQR) family, in mediating rapid, nongenomic (non-classical) progestogen actions has been extensively studied since their identification 20 years ago ...
Thomas P.
europepmc +2 more sources
Expression of estrogen and progesterone receptors in astrocytomas: a literature review
Clinics, 2016 Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones.
Cléciton Braga Tavares +11 more
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Progesterone Receptors, their Isoforms and Progesterone Regulated Transcription [PDF]
Molecular and Cellular Endocrinology, 2011 This review discusses mechanisms by which progesterone receptors (PR) regulate transcription. We examine available data in different species and tissues regarding: 1) regulation of PR levels; and 2) expression profiling of progestin-regulated genes by ...
Britta M. Jacobsen, K. Horwitz
semanticscholar +3 more sources
Membrane Progesterone Receptors (mPRs/PAQRs) Are Going beyond Its Initial Definitions [PDF]
Membranes, 2023 Progesterone (PRG) is a key cyclical reproductive hormone that has a significant impact on female organs in vertebrates. It is mainly produced by the corpus luteum of the ovaries, but can also be generated from other sources such as the adrenal cortex ...
Justin Aickareth +4 more
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Limbic progesterone receptors regulate spatial memory [PDF]
Scientific Reports, 2023 Progesterone and its receptors (PRs) participate in mating and reproduction, but their role in spatial declarative memory is not understood. Male mice expressed PRs, predominately in excitatory neurons, in brain regions that support spatial memory, such ...
Suchitra Joshi +2 more
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Progress in Neurobiology, 2014 Progesterone is commonly considered as a female reproductive hormone and is well-known for its role in pregnancy. It is less well appreciated that progesterone and its metabolite allopregnanolone are also male hormones, as they are produced in both sexes
Michael Schumacher +2 more
exaly +2 more sources
The Neandertal Progesterone Receptor [PDF]
Molecular Biology and Evolution, 2020 Abstract The hormone progesterone is important for preparing the uterine lining for egg implantation and for maintaining the early stages of pregnancy. The gene encoding the progesterone receptor (PGR) carries introgressed Neandertal haplotypes with two missense substitutions and a mobile Alu element.
Hugo Zeberg, Janet Kelso, Svante Pääbo
openaire +3 more sources
Endometrial Progesterone and Estrogen Receptors in Relation to Hormonal Levels in Women with Unexplained Recurrent Miscarriage [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2023 Objective Recurrent miscarriage has been linked to hormonal disturbance due to dysregulation of its receptors rather than to the availability of the hormone.
Ihab Adel Gomaa +4 more
doaj +1 more source
Immunohistochemical expression of progesterone receptor and C-erb-B2 in cervical squamous cell carcinoma and epithelial dysplasia [PDF]
Journal of Clinical and Investigative Surgery, 2021 Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results.
Emine Zeynep Tarini +1 more
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