Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes* [PDF]
Endocrinology, 2000 For rat pituitary cells, progesterone receptor (PR) protein localizes to gonadotropes and PR messenger RNA is induced by E2 and rapidly but transiently down-regulated by progesterone. Here we quantitatively establish the down-regulatory effect of progesterone on PR protein and evaluate possible mechanisms.
J L, Turgeon, D W, Waring
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Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Acta Dermato-Venereologica, 2018 Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng +6 more
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Changes in ovaries and uterus after aglepristone administration in the third week of luteal phase of non-pregnant bitches. [PDF]
PLoS ONE, 2015 The mechanism of aglepristone action in the placentation time in the bitch remains unclear. The aim of this study was to describe the mechanism by which aglepristone influences ovaries and uterus and to measure the levels of steroid sex hormones in non ...
Kamil Kacprzak +5 more
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Estrogen and Progesterone Receptors in Human Colorectal Tumour Cells (Study of 70 Cases)
The International Journal of Biological Markers, 1988 Estrogen and progesterone receptors were studied in 70 cases of human colorectal cancer by a cytochemical technique. 28.5% of the cases were estrogen-receptor positive and 42.8% progesterone-receptor positive.
G. Bracali +5 more
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Rodent Models of Non-classical Progesterone Action Regulating Ovulation
Frontiers in Endocrinology, 2017 It is becoming clear that steroid hormones act not only by binding to nuclear receptors that associate with specific response elements in the nucleus but also by binding to receptors on the cell membrane. In this newly discovered manner, steroid hormones
Melinda A. Mittelman-Smith +3 more
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MicroRNAs and Progesterone Receptor Signaling in Endometriosis Pathophysiology
Cells, 2022 Endometriosis is a significant disease characterized by infertility and pelvic pain in which endometrial stromal and glandular tissue grow in ectopic locations.
Warren B. Nothnick
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Steroid hormone bioavailability is controlled by the lymphatic system
Scientific Reports, 2021 The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restriction, and in
Rahel Klossner +9 more
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Steroids, Pregnancy and Fetal Development
Frontiers in Immunology, 2020 Maternal glucocorticoids critically rise during pregnancy reaching up to a 20-fold increase of mid-pregnancy concentrations. Concurrently, another steroid hormone, progesterone, increases.
Maria Emilia Solano, Petra Clara Arck
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Post-translational Modifications of the Progesterone Receptors
Journal of Steroid Biochemistry and Molecular Biology, 2013 Progesterone plays a key role in the development, differentiation and maintenance of female reproductive tissues and has multiple non-reproductive neural functions.
Hany A. Abdel-Hafiz, K. Horwitz
semanticscholar +1 more source
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
International Journal of Molecular Sciences, 2019 In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window of receptivity.
R. Marquardt +3 more
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