Results 11 to 20 of about 2,874,490 (301)

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

Archives of Pathology & Laboratory Medicine, 2010
Purpose To develop a guideline to improve the accuracy of immunohistochemical (IHC) estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the utility of these receptors as predictive markers.
M. Hammond, Daniel F. Hayes, M. Dowsett, D. C. Allred, Karen L. Hagerty, S. Badve, P. Fitzgibbons, G. Francis, N. Goldstein, M. Hayes, David G. Hicks, S. Lester, R. Love, Pamela B. Mangu, L. McShane, K. Miller, C. Osborne, S. Paik, J. Perlmutter, A. Rhodes, H. Sasano, Jared N. Schwartz, F. C. Sweep, S. Taube, E. Torlakovic, P. Valenstein, G. Viale, D. Visscher, T. Wheeler, R. B. Williams, J. Wittliff, Antonio C. Wolff   +31 more
semanticscholar   +3 more sources

Progestin receptor-mediated reduction of anxiety-like behavior in male rats. [PDF]

PLoS ONE, 2008
BACKGROUND: It is well known progesterone can have anxiolytic-like effects in animals in a number of different behavioral testing paradigms. Although progesterone is known to influence physiology and behavior by binding to classical intracellular ...
Catherine J Auger, Robin M Forbes-Lorman
doaj   +1 more source

Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland [PDF]

Archives of Biological Sciences, 2011
The nature and extent of estrogen and progesterone action on the lacrimal gland is not known, and neither are the targets for their action. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal glands in both sexes
Gligorijević Jasmina, Krstić M., Babić Gordana   +2 more
doaj   +1 more source

Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone

Molecular Pain, 2022
Orofacial pain disorders are predominately experienced by women. Progesterone, a major ovarian hormone, is neuroprotective and antinociceptive. We recently reported that progesterone attenuates estrogen-exacerbated orofacial pain behaviors, yet it ...
Rebecca S Hornung, Namrata GR Raut, Daisy J Cantu, Lauren M Lockhart, Dayna L Averitt   +4 more
doaj   +1 more source

Data on RT-qPCR assay of nuclear progesterone receptors (nPR), membrane progesterone receptors (mPR) and progesterone receptor membrane components (PGRMC) from human uterine endometrial tissue and cancer cells of the Uterine Cervix

Data in Brief, 2020
A previous investigation showed that the endometrium normalized in women with endometrial hyperplasia after three months treatment with high dose levonorgestrel IUS (intrauterine system) [1]. The effect was maintained even if immunohistochemical analyses
Natalia Smaglyukova, Elise Thoresen Sletten, Anne Ørbo, Georg Sager   +3 more
doaj   +1 more source

A novel therapeutic approach for treatment of catamenial epilepsy

Neurobiology of Disease, 2018
Many women with epilepsy experience perimenstrual seizure exacerbation, referred to as catamenial epilepsy. There is no effective treatment for this condition, proposed to result from withdrawal of neurosteroid-mediated effects of progesterone.
Suchitra Joshi, Huayu Sun, Karthik Rajasekaran, John Williamson, Edward Perez-Reyes, Jaideep Kapur   +5 more
doaj   +1 more source

Morphological Characteristics and Expression of Estrogen and Progesterone Receptors in the Canine Endometrium During the Estrus Cycle, Cystic Endometrial Hyperplasia and Pyometra

Acta Veterinaria, 2018
The estrus cycle of bitches is divided into four phases: proestrus, estrus, diestrus and anestrus, during which different morphological changes, and also cyclic changes of estrogen and progesterone receptors are present.
Marinković Darko, Aničić Milan, Vakanjac Slobodanka, Nedić Svetlana, Magaš Vladimir   +4 more
doaj   +1 more source

Progesterone signaling mechanisms in brain and behavior

Frontiers in Endocrinology, 2012
Steroid hormone, progesterone, modulates neuroendocrine functions in the central nervous system resulting in alterations in physiology and behavior.
Shaila eMani, Mario G Oyola
doaj   +1 more source

Membrane progesterone receptor beta (mPRβ/Paqr8) promotes progesterone-dependent neurite outgrowth in PC12 neuronal cells via non-G protein-coupled receptor (GPCR) signaling

Scientific Reports, 2017
Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors.
Mayu Kasubuchi, Keita Watanabe, Kanako Hirano, Daisuke Inoue, Xuan Li, Kazuya Terasawa, Morichika Konishi, Nobuyuki Itoh, Ikuo Kimura   +8 more
doaj   +1 more source

Reproductive functions of the progesterone receptor

Journal of the Society for Gynecologic Investigation, 2000
The steroid hormone progesterone plays a central role in the reproductive events associated with pregnancy establishment and maintenance. Physiological effects of progesterone are mediated by interaction of the hormone with specific intracellular progesterone receptors (PRs) that are expressed as two protein isoforms, PR-A and PR-B. Both proteins arise
Conneely, O.M., Mulac-Jeričević, Biserka, DeMayo, F., Lydon, J.P., O'Malley, B.W.   +4 more
openaire   +3 more sources