Frontiers in Endocrinology, 2023 The dual aquaporin (Aqp1ab1/Aqp1ab2)-mediated hydration of marine teleost eggs, which occurs during oocyte meiosis resumption (maturation), is considered a key adaptation underpinning their evolutionary success in the oceans.
Alba Ferré +6 more
doaj +1 more source
Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells [PDF]
, 2005 Interactions between steroid hormone receptors and signal transducer and activator of transcription (Stat)-mediated signaling pathways have already been described.
Carnevale, Romina Paula +10 more
core +3 more sources
Cancer Medicine, 2023 Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang +6 more
doaj +1 more source
Breast Cancer Risk with Progestin Subdermal Implants: A Challenge in Patients Counseling
Frontiers in Endocrinology, 2021 There is a steady global rise in the use of progestin subdermal implants, where use has increased by more than 20 times in the past two decades. BC risk has been reported with the older progestin only methods such as oral pills, injectables, and ...
Ghada Mohammed +6 more
doaj +1 more source
The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]
, 2017 Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D +12 more
core +3 more sources
Frontiers in Oncology, 2022 The Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE) is a molecular classification system that identifies endometrial cancer (EC) into four prognostically distinct subtypes: POLE-mutated, mismatch repair deficiency (MMR-D), p53 wild ...
Xuting Ran +5 more
doaj +1 more source
Fertility-sparing treatment in early endometrial cancer: current state and future strategies [PDF]
Obstetrics & Gynecology Science, 2020 Endometrial cancer (EC) is the fifth most common cancer in women worldwide. Global estimates show rising incidence rates in both developed and developing countries.
Andreas Obermair +11 more
doaj +1 more source
Early postpartum luteal function after treatment with progestin and(or) gonadotropin-releasing hormone in dairy cattle [PDF]
, 1988 Progestin (Norgestomet®) and(or) repeated low-dose infusions of GnRH (Cystorelin@) influenced the lifespan of the first corpus luteum after an induced ovulation. Holstein cows (n=32) were assigned at calving to four groups. Cows were treated with blank
Mee, M.O., Stevenson, Jeffrey S.
core +2 more sources
Prenatal Progestin Exposure Is Associated With Autism Spectrum Disorders
Frontiers in Psychiatry, 2018 We have previously reported that prenatal progestin exposure induces autism-like behavior in offspring through ERβ (estrogen receptor β) suppression in the brain, indicating that progestin may induce autism spectrum disorders (ASD). In this study, we aim
Ling Li +17 more
doaj +1 more source
Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]
, 2016 This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo +5 more
core +1 more source