Results 171 to 180 of about 11,052 (225)
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Molecular Biology, 2016
Progesterone and its analogs may exert opposite effects on cell proliferation, apoptosis, and epithelial-mesenchymal transition, leading to higher cell motility and metastasis. Their ultimate effect is determined by a number of factors: the structure and concentration of the steroid, its affinity for various forms of steroid hormone receptors ...
T A, Shchelkunova, I A, Morozov
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Progesterone and its analogs may exert opposite effects on cell proliferation, apoptosis, and epithelial-mesenchymal transition, leading to higher cell motility and metastasis. Their ultimate effect is determined by a number of factors: the structure and concentration of the steroid, its affinity for various forms of steroid hormone receptors ...
T A, Shchelkunova, I A, Morozov
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Progestins in HRT: Sufferance or desire?
Maturitas, 2009While the benefits of progestins in hormonal replacement therapy are well recognized as far as endometrial protection is concerned the data on breast tissue and the cardiovascular system are contentious. Following the Women's Health Initiative study, the Million Women Study and The Women's International Study of Long-duration (O)estrogen after ...
Skouby, Sven O, Jespersen, Joergen
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Maturitas, 1996
The history of progesterone and hormone replacement therapy goes back to 1934 when Butenandt obtained crystalline progesterone and Kaufmann started to treat ovariectomized women with both estrogens and progesterone (Table 1). Today synthetic perorally active 19-nortestosterone and 17-alpha-hydroxyprogesterone derivatives are used in addition to ...
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The history of progesterone and hormone replacement therapy goes back to 1934 when Butenandt obtained crystalline progesterone and Kaufmann started to treat ovariectomized women with both estrogens and progesterone (Table 1). Today synthetic perorally active 19-nortestosterone and 17-alpha-hydroxyprogesterone derivatives are used in addition to ...
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Steroids, 2000
Progestin implants for contraception are highly effective, safe, and the most convenient choice for many women. Progestin implants currently on the market, preparing for launch, or under investigation are reviewed here. Their basic galenic and pharmacokinetic features, as well as their contraceptive effectiveness, are described.
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Progestin implants for contraception are highly effective, safe, and the most convenient choice for many women. Progestin implants currently on the market, preparing for launch, or under investigation are reviewed here. Their basic galenic and pharmacokinetic features, as well as their contraceptive effectiveness, are described.
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Journal of Midwifery & Women's Health, 2002
ABSTRACTProgestin contraceptives offer unique advantages, allowing the clinician to tailor optimum regimens for selected women. This article reviews the various progestational drugs, regimens, and delivery systems available presently and in development, with reference to the clinical benefits and limitations of each method.
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ABSTRACTProgestin contraceptives offer unique advantages, allowing the clinician to tailor optimum regimens for selected women. This article reviews the various progestational drugs, regimens, and delivery systems available presently and in development, with reference to the clinical benefits and limitations of each method.
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The androgenicity of progestins
The American Journal of Medicine, 1995All steroid hormones are structurally similar, but relatively minor differences cause profound alterations in biochemical activity. The 21-carbon series (pregnane nucleus) includes the corticoids and the true progestins (e.g., medroxyprogesterone acetate).
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The Journal of Steroid Biochemistry and Molecular Biology, 1999
While the benefits of progestin use in hormone replacement therapy (HRT) are well recognised as far as endometrial protection is concerned, their risks and drawbacks have generated controversial articles. The data related to the progestin effect on breast tissue has been interpreted differently from country to country. However it has been admitted that,
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While the benefits of progestin use in hormone replacement therapy (HRT) are well recognised as far as endometrial protection is concerned, their risks and drawbacks have generated controversial articles. The data related to the progestin effect on breast tissue has been interpreted differently from country to country. However it has been admitted that,
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Contraception, 2001
There is considerable confusion concerning the use of the term "progestin" in referring to progestational compounds. Such term is often restricted to progestational agents that are synthetic and excludes progesterone which is a natural compound. In 1930 when progesterone had not yet been isolated the term "progestin" was proposed for the name of this
F Z, Stanczyk, M R, Henzl
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There is considerable confusion concerning the use of the term "progestin" in referring to progestational compounds. Such term is often restricted to progestational agents that are synthetic and excludes progesterone which is a natural compound. In 1930 when progesterone had not yet been isolated the term "progestin" was proposed for the name of this
F Z, Stanczyk, M R, Henzl
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2008
Fil: Elizalde, Patricia Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental.
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Fil: Elizalde, Patricia Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental.
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Drospirenone: a novel progestin
Expert Opinion on Pharmacotherapy, 2007Drospirenone is a novel progestin available in combined oral contraceptives and menopausal hormonal therapy. Similar to its parent compound spirolactone, an analog of spironolactone, drospirenone has antimineralocorticoid and antiandrogenic activity.
Andrea J, Rapkin, Sharon A, Winer
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