Results 191 to 200 of about 10,432 (237)
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Drospirenone: a novel progestin
Expert Opinion on Pharmacotherapy, 2007Drospirenone is a novel progestin available in combined oral contraceptives and menopausal hormonal therapy. Similar to its parent compound spirolactone, an analog of spironolactone, drospirenone has antimineralocorticoid and antiandrogenic activity.
Andrea J, Rapkin, Sharon A, Winer
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On the mechanism of action of progestins
Acta Endocrinologica, 1981Abstract. The effect of two synthetic injectable progestins, norethisterone oenanthate3 (NET-e) and medroxyprogesterone acetate (MPA) upon the hypothalamic pituitary unit was evaluated in post-menopausal women (PMW) and in castrated individuals with androgen un-responsiveness in order to gain insight into their mechanism of gonadotrophin inhibition ...
G, Pérez-Palacios +4 more
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Progestins and Skeletal Maturation
New England Journal of Medicine, 1963THE association of virilization of the female fetus with the administration of certain progestins during pregnancy is now well recognized.
S, BREIBART +2 more
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Breast Disease, 2006
Progesterone (P) regulates proliferation and differentiation in the normal mammary gland in mouse, rat and human. Progesterone has also been implicated in the etiology and pathogenesis of human breast cancer. The focus of this review is on recent advances in understanding the role of the progesterone receptor (PR) and functional significance of PR ...
Mark, Aupperlee +3 more
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Progesterone (P) regulates proliferation and differentiation in the normal mammary gland in mouse, rat and human. Progesterone has also been implicated in the etiology and pathogenesis of human breast cancer. The focus of this review is on recent advances in understanding the role of the progesterone receptor (PR) and functional significance of PR ...
Mark, Aupperlee +3 more
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Presse medicale (Paris, France : 1983), 1983
Progesterone exerts most of its actions through its specific receptors. However, synthetic progestins and progesterone itself may bind with other steroid receptors, thus producing a variety of effects. For instance, some nonsteroid derivatives produce virilizing effects by acting on testosterone receptors.
R, Sitruk-Ware, P, Mauvais-Jarvis
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Progesterone exerts most of its actions through its specific receptors. However, synthetic progestins and progesterone itself may bind with other steroid receptors, thus producing a variety of effects. For instance, some nonsteroid derivatives produce virilizing effects by acting on testosterone receptors.
R, Sitruk-Ware, P, Mauvais-Jarvis
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Minerva ginecologica, 2011
Progestins are a group of different compounds sharing the ability to induce secretory changes on a endometrium pretreated with estrogen, while they are different in some abilities, for example the interaction with receptors other than progestin receptor, as androgenic or mineralocorticoid receptor. Some progestins have antiandrogenic properties and are
S, Lello, L, Colonna
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Progestins are a group of different compounds sharing the ability to induce secretory changes on a endometrium pretreated with estrogen, while they are different in some abilities, for example the interaction with receptors other than progestin receptor, as androgenic or mineralocorticoid receptor. Some progestins have antiandrogenic properties and are
S, Lello, L, Colonna
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Progesterone-Progestin Receptors
1974A correlation between binding to the progestin-specific uterine cytosol receptor and with well-defined facets of progesterone action was established. Structurally similar derivatives of norprogesterone and nortestosterone were compared. Binding was measured in vitro by determining their competitive effect on the progestin-tagged uterine cytosol ...
J P, Raynaud +2 more
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Progestins and their effects on the breast
Maturitas, 2003Nowadays, when the available scientific data on the in vivo effects of progestins on mammary gland tissue remain controversial, it is of utmost importance to establish adequate criteria to evaluate their actions. One of the reasons for this situation is that a variety of progestins have been studied using a number of different study designs.
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