Results 181 to 190 of about 11,052 (225)
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On the mechanism of action of progestins
Acta Endocrinologica, 1981Abstract. The effect of two synthetic injectable progestins, norethisterone oenanthate3 (NET-e) and medroxyprogesterone acetate (MPA) upon the hypothalamic pituitary unit was evaluated in post-menopausal women (PMW) and in castrated individuals with androgen un-responsiveness in order to gain insight into their mechanism of gonadotrophin inhibition ...
G, Pérez-Palacios +4 more
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Minerva ginecologica, 2011
Progestins are a group of different compounds sharing the ability to induce secretory changes on a endometrium pretreated with estrogen, while they are different in some abilities, for example the interaction with receptors other than progestin receptor, as androgenic or mineralocorticoid receptor. Some progestins have antiandrogenic properties and are
S, Lello, L, Colonna
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Progestins are a group of different compounds sharing the ability to induce secretory changes on a endometrium pretreated with estrogen, while they are different in some abilities, for example the interaction with receptors other than progestin receptor, as androgenic or mineralocorticoid receptor. Some progestins have antiandrogenic properties and are
S, Lello, L, Colonna
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Presse medicale (Paris, France : 1983), 1983
Progesterone exerts most of its actions through its specific receptors. However, synthetic progestins and progesterone itself may bind with other steroid receptors, thus producing a variety of effects. For instance, some nonsteroid derivatives produce virilizing effects by acting on testosterone receptors.
R, Sitruk-Ware, P, Mauvais-Jarvis
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Progesterone exerts most of its actions through its specific receptors. However, synthetic progestins and progesterone itself may bind with other steroid receptors, thus producing a variety of effects. For instance, some nonsteroid derivatives produce virilizing effects by acting on testosterone receptors.
R, Sitruk-Ware, P, Mauvais-Jarvis
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The Metabolic Influence of Progestins
1971Publisher Summary This chapter discusses the effects of progesterone and synthetic progestins. The metabolic effects of synthetic progestins can be related to their pharmacological uses, including the unwanted side effects of the oral contraceptive drug mixtures. The most completely described influence of the progestins is that exerted on protein and
R L, Landau, J T, Poulos
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Progesterone-Progestin Receptors
1974A correlation between binding to the progestin-specific uterine cytosol receptor and with well-defined facets of progesterone action was established. Structurally similar derivatives of norprogesterone and nortestosterone were compared. Binding was measured in vitro by determining their competitive effect on the progestin-tagged uterine cytosol ...
J P, Raynaud +2 more
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Progestin, Thrombophlebitis and Migraine
Acta Medica Scandinavica, 1967Attention is called to the relationship of oral contraceptives (especially the progestogen factor) and occurrence of thromboembolism. A case is reported of a woman who experienced migraine and thromophlebitis every time she ingested oral contraceptives which she took for 3 months.
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The Selectivity of a New Progestin
Acta Obstetricia et Gynecologica Scandinavica, 1990Norgestimate is a new progestin developed for use with ethinyl estradiol as a combination oral contraceptive. It binds to rabbit uterine progestational receptors and in the oral form stimulates a progestational endometrial effect in rabbits. Norgestimate also exerts a direct effect on target organs, stimulating the endometrium in rabbits when injected ...
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