Results 211 to 220 of about 32,229 (277)
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Progesterone, progestins and the breast in menopause treatment
Climacteric, 2018Breast cancer is the main risk associated with menopause hormone therapy (MHT). It is a hormone-dependent cancer. In postmenopausal women, about 80% of cases are estradiol receptor-positive.
A. Gompel, G. Plu-Bureau
semanticscholar +1 more source
Maturitas, 1996
The history of progesterone and hormone replacement therapy goes back to 1934 when Butenandt obtained crystalline progesterone and Kaufmann started to treat ovariectomized women with both estrogens and progesterone (Table 1). Today synthetic perorally active 19-nortestosterone and 17-alpha-hydroxyprogesterone derivatives are used in addition to ...
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The history of progesterone and hormone replacement therapy goes back to 1934 when Butenandt obtained crystalline progesterone and Kaufmann started to treat ovariectomized women with both estrogens and progesterone (Table 1). Today synthetic perorally active 19-nortestosterone and 17-alpha-hydroxyprogesterone derivatives are used in addition to ...
openaire +2 more sources
Do progestins contribute to (anti-)androgenic activities in aquatic environments?
Environmental Pollution, 2018Unknown compounds with (anti-)androgenic activities enter the aquatic environment via municipal wastewater treatment plants (WWTPs). Progestins are well-known environmental contaminants capable of interfering with androgen receptor (AR) signaling pathway.
P. Šauer +8 more
semanticscholar +1 more source
Steroids, 2000
Progestin implants for contraception are highly effective, safe, and the most convenient choice for many women. Progestin implants currently on the market, preparing for launch, or under investigation are reviewed here. Their basic galenic and pharmacokinetic features, as well as their contraceptive effectiveness, are described.
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Progestin implants for contraception are highly effective, safe, and the most convenient choice for many women. Progestin implants currently on the market, preparing for launch, or under investigation are reviewed here. Their basic galenic and pharmacokinetic features, as well as their contraceptive effectiveness, are described.
openaire +2 more sources
Journal of Midwifery & Women's Health, 2002
ABSTRACTProgestin contraceptives offer unique advantages, allowing the clinician to tailor optimum regimens for selected women. This article reviews the various progestational drugs, regimens, and delivery systems available presently and in development, with reference to the clinical benefits and limitations of each method.
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ABSTRACTProgestin contraceptives offer unique advantages, allowing the clinician to tailor optimum regimens for selected women. This article reviews the various progestational drugs, regimens, and delivery systems available presently and in development, with reference to the clinical benefits and limitations of each method.
openaire +2 more sources
Molecular Biology, 2016
Progesterone and its analogs may exert opposite effects on cell proliferation, apoptosis, and epithelial-mesenchymal transition, leading to higher cell motility and metastasis. Their ultimate effect is determined by a number of factors: the structure and concentration of the steroid, its affinity for various forms of steroid hormone receptors ...
T A, Shchelkunova, I A, Morozov
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Progesterone and its analogs may exert opposite effects on cell proliferation, apoptosis, and epithelial-mesenchymal transition, leading to higher cell motility and metastasis. Their ultimate effect is determined by a number of factors: the structure and concentration of the steroid, its affinity for various forms of steroid hormone receptors ...
T A, Shchelkunova, I A, Morozov
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Clinical pharmacology of progestins
Minerva Obstetrics and Gynecology, 2022In this paper, we report general pharmacological profile and major biological activities of natural progesterone (P) and progestins. The aim of this article consists of synthesizing the principal aspects of pharmacology and metabolism of P and progestins related to the clinical consequences of their use.We review scientific literature on the topic ...
Capozzi, Anna +2 more
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Classification and pharmacology of progestins
Maturitas, 2003A. Schindler +6 more
exaly +2 more sources
2008
Fil: Elizalde, Patricia Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental.
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Fil: Elizalde, Patricia Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental.
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Progesterone-Progestin Receptors
1974A correlation between binding to the progestin-specific uterine cytosol receptor and with well-defined facets of progesterone action was established. Structurally similar derivatives of norprogesterone and nortestosterone were compared. Binding was measured in vitro by determining their competitive effect on the progestin-tagged uterine cytosol ...
J P, Raynaud +2 more
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