Results 71 to 80 of about 295,913 (316)
Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis [PDF]
Background With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and biochemical ...
Granit, Volkan +14 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Prognostic Biomarkers in Sepsis
Eurasian Journal of Critical Care, 2023 We read with great interest the article titled “Evaluation and Diagnostic Effectiveness of Hemogram, Biochemistry and Inflammatory Markers (Immature Granulocyte, Procalcitonin, CRP, NLR, PLR) in Patients with Sepsis” prepared by Gedik and Çiftçioğlu and published in the second issue of your journal in 2023.
openaire +2 more sources
Efficacy of Presepsin as a Biomarker of Sepsis and Its Prognostic Value for Prediction of Mortality
, 2020 Aim:We aimed to determine the efficacy of presepsin (PRE) as a biomarker of sepsis and to asssess its prognostic value for prediction of mortality were determined.Methods:Selected clinical data of 21 patients admitted to intensive care unit for systemic ...
İbrahim Akkoç +6 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2023 Bowen Li,* Jinghang Liu,* Liangzhi Xu, Qi Xu, Zhaohui Liu, Tiande Liu Department of General Surgery, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330000, People’s Republic of China*These authors contributed ...
Xu L, Liu J, Liu Z, Xu Q, Li B, Liu T
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Non‐invasive prognostic protein biomarker signatures associated with colorectal cancer
EMBO Molecular Medicine, 2015 The current management of colorectal cancer (CRC) would greatly benefit from non‐invasive prognostic biomarkers indicative of clinicopathological tumor characteristics.
Silvia Surinova +7 more
doaj +1 more source
Psf3 is a prognostic biomarker in lung adenocarcinoma [PDF]
Lung Cancer, 2013 Psf3 is a member of the evolutionarily conserved heterotetrameric complex GINS (Go-Ichi-Ni-San), which consists of Sld5, Psf1, Psf2, and Psf3. Previous studies have suggested that some GINS complex members are upregulated in cancer, but the status of Psf3 expression in lung adenocarcinoma has not been investigated.
Daisuke, Hokka +9 more
openaire +2 more sources