Results 251 to 260 of about 863,398 (307)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

PREDICT breast v4.0: an update to the PREDICT breast prognostic model. [PDF]

BMC Res Notes
Pharoah PDP, Hsiao YW, Wishart GC, Peng PC.   +3 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

A prognostic model based on immune cells in tumor microenvironment to predict prognosis in endometrial cancer. [PDF]

BMC Cancer
Li L, Dong Y, Li H, Dai Y, Zhai Z, Zhang X, Shen D, Wang J.   +7 more
europepmc   +1 more source

A Glycerophospholipid Metabolism-Based Prognostic Model Guides Osteosarcoma Therapy. [PDF]

Transl Oncol
Wen Y, Wang D, Wang H, Zhao J, Yao L, Zhang J, Chen B.   +6 more
europepmc   +1 more source

Integrated ICD-based subtyping and prognostic model reveal KCNN4 as a novel therapeutic target in NSCLC. [PDF]

Discov Oncol
Yang Z, Yang Q, Li S, Han R, He H, Zhang R, Li H, Li Y, Cheng P, Liu X.   +9 more
europepmc   +1 more source

A novel prognostic model for colon adenocarcinoma based on cofactor and vitamin metabolism-related genes. [PDF]

Transl Cancer Res
Yang Q, Du Z, Yu H, Liu T.
europepmc   +1 more source

Serum Lipid-Based Prognostic Model for Advanced Intrahepatic Cholangiocarcinoma Under Chemo-Immunotherapy. [PDF]

J Hepatocell Carcinoma
Jiang C, Long K, Fang T, Li W, Yang L, Chai P, Tao J, Long K.   +7 more
europepmc   +1 more source

A prognostic model based on metabolic indicators for recurrent acute pancreatitis in hypertriglyceridemia patients: a retrospective cohort study. [PDF]

Ann Med
Wang Z, Liu Y, Ren P, Zhu G, Zhang G, Zhang X, Sun S, Shi A, Lin Y, Qu H.   +9 more
europepmc   +1 more source

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Prognostic modeling in biliary diseases

Current Opinion in Gastroenterology, 2023
Purpose of review To discuss the prognostic models for the cholestatic diseases focusing on primary sclerosing cholangitis and primary biliary cholangitis. Recent findings Noninvasive prognostic models that outperform alkaline phosphatase and Mayo Risk Score have been developed to ...
Camelia, Ciobanu, Mark W, Russo
openaire   +2 more sources