Results 41 to 50 of about 22,923,614 (357)

Personalized treatment of brain metastases: Evolving survival prediction models may benefit from evaluation of serum tumor markers (narrative review)

Frontiers in Oncology, 2022
Treatment of a limited number of brain metastases (oligometastases) might include complex and sometimes invasive approaches, e.g. neurosurgical resection followed by post-operative stereotactic radiotherapy, and thus, correct identification of patients ...
Carsten Nieder, Carsten Nieder, Nicolaus H. Andratschke, Anca L. Grosu   +3 more
doaj   +1 more source

Echocardiography combined with cardiopulmonary exercise testing for the prediction of outcome in idiopathic pulmonary arterial hypertension [PDF]

, 2016
BACKGROUND: Right ventricular (RV) function is a major determinant of exercise intolerance and outcome in idiopathic pulmonary arterial hypertension (IPAH). The aim of the study was to evaluate the incremental prognostic value of echocardiography of the
Badagliacca, Roberto, Fedele, Francesco, Giannetta, E, Manzi, G, Naeije, R, Palange, Paolo, Papa, S, Pezzuto, Beatrice, Poscia, Roberto, Sciomer, S, Valli, G, Vizza, Carmine Dario   +11 more
core   +1 more source

Vemurafenib inhibits immune escape biomarker BCL2A1 by targeting PI3K/AKT signaling pathway to suppress breast cancer

Frontiers in Oncology, 2022
ObjectivesTo investigate the role of immune escape encoding genes on the prognosis of BC, and to predict the novel targeting agents.MethodsHuman immune genes and immune escape encoding genes were obtained from the IMMPORT database and the previous study.
Yalan Dai, Liqiong Yang, Liqiong Yang, Abass Sakandar, Duoli Zhang, Duoli Zhang, Fukuan Du, Fukuan Du, Fukuan Du, Xinyi Zhang, Linglin Zou, Yueshui Zhao, Yueshui Zhao, Yueshui Zhao, Jigang Wang, Zhenhua Zhang, Xu Wu, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Mingxing Li, Xiao Ling, Lei Yu, Lishu Dong, Jing Shen, Jing Shen, Jing Shen, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Qinglian Wen   +31 more
doaj   +1 more source

A prognostic model based on clusters of molecules related to epithelial–mesenchymal transition for idiopathic pulmonary fibrosis

Frontiers in Genetics, 2023
Background: Most patients with idiopathic pulmonary fibrosis (IPF) have poor prognosis; Effective predictive models for these patients are currently lacking.
Jiarui Zhao, Can Wang, Rui Fan, Xiangyang Liu, Wei Zhang   +4 more
doaj   +1 more source

The impact of loco-regional recurrences on metastatic progression in early-stage breast cancer: a multistate model [PDF]

, 2009
To study whether the effects of prognostic factors associated with the occurrence of distant metastases (DM) at primary diagnosis change after the incidence of loco-regional recurrences (LRR) among women treated for invasive stage I or II breast cancer ...
A Fourquet, AC Voogd, B Fisher, B Fisher, B Fisher, C Vrieling, C. J. van de Velde, D Cowen, E Touboul, Early Breast Cancer Trialists’ Collaborative Group, G Coulombe, G. H. de Bock, H Bartelink, H Kemperman, H Putter, H. Bartelink, H. Putter, HM Nielsen, I Soerjomataram, J Dongen Van, J Engel, J Hage Van der, J Hage Van der, J Ragaz, J. A. van der Hage, J. Bonnema, JA Dongen Van, JA Dongen Van, JG Nes Van, L Livi, M Clarke, M Leest Van der, M Sangen Van der, MA Bollet, N Kroman, P Broet, PC Clahsen, PH Elkhuizen, PH Elkhuizen, R Arriagada, R Arriagada, RS Punglia, U Veronesi, WS Halsted   +43 more
core   +4 more sources

Development of a prognostic model for mortality in COVID-19 infection using machine learning

Modern Pathology, 2020
Coronavirus disease 2019 (COVID-19) is a novel disease resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has quickly risen since the beginning of 2020 to become a global pandemic. As a result of the rapid
Adam L. Booth, E. Abels, P. McCaffrey
semanticscholar   +1 more source

A prognostic model for cervical cancer based on ferroptosis-related genes

Frontiers in Endocrinology, 2022
BackgroundFerroptosis is widely involved in the occurrence and development of various cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear.MethodsBased on the expressions of ferroptosis-related genes, a prognostic ...
Huijun Du, Huijun Du, Yumei Tang, Yumei Tang, Xiaoying Ren, Xiaoying Ren, Fan Zhang, Fan Zhang, Wei Yang, Wei Yang, Le Cheng, Yunan Gao, Yunan Gao   +12 more
doaj   +1 more source

Clinical prediction models to inform individualized decision-making in subfertile couples : a stratified medicine approach [PDF]

, 2014
Funding This work was supported by a Chief Scientist Office Postdoctoral Training Fellowship in Health Services Research and Health of the Public Research (Ref PDF/12/06).
Bhattacharya, S., McLernon, D.J., Mol, B.W.J., Steyerberg, E.W., te Velde, E.R.   +4 more
core   +3 more sources

Construction and validation of a glycolysis-related lncRNA signature for prognosis prediction in Stomach Adenocarcinoma

Frontiers in Genetics, 2022
Background: Glycolysis is closely related to the occurrence and progression of gastric cancer (GC). Currently, there is no systematic study on using the glycolysis-related long non-coding RNA (lncRNA) as a model for predicting the survival time in ...
Tianyou Liao, Yan Lu, Wangji Li, Wangji Li, Kang Wang, Kang Wang, Yanxiang Zhang, Zhentao Luo, Yongle Ju, Yongle Ju, Manzhao Ouyang, Manzhao Ouyang   +11 more
doaj   +1 more source

Large-scale bulk RNA-seq analysis defines immune evasion mechanism related to mast cell in gliomas

Frontiers in Immunology, 2022
Accumulating evidence has demonstrated that the immune cells have an emerging role in controlling anti-tumor immune responses and tumor progression. The comprehensive role of mast cell in glioma has not been illustrated yet.
Rui Chen, Wantao Wu, Wantao Wu, Wantao Wu, Tao Liu, Tao Liu, Tao Liu, Yihan Zhao, Yihan Zhao, Yihan Zhao, Yifan Wang, Yifan Wang, Hao Zhang, Hao Zhang, Zeyu Wang, Zeyu Wang, Ziyu Dai, Ziyu Dai, Xiaoxi Zhou, Xiaoxi Zhou, Peng Luo, Jian Zhang, Zaoqu Liu, Li-Yang Zhang, Li-Yang Zhang, Quan Cheng, Quan Cheng   +26 more
doaj   +1 more source