Results 41 to 50 of about 866,858 (352)

In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma

Frontiers in Immunology
BackgroundCurrently, adequate treatment and prognostic prediction means for Hepatocellular Carcinoma (HCC) haven’t entered into medical vision. Tanshinone IIA (TanIIA) is a natural product, which can be utilized as a potential treatment of HCC due to its
Lichao Qian, Zhongchi Xu, Tianjiong Luo, Zhao Gao, Kun Cheng, Xiaolong He, Zhongai Zhang, Shuai Ren, Yinxing Zhu   +8 more
doaj   +1 more source

Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysis

Frontiers in Oncology, 2022
Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. The bone marrow (BM) microenvironment in AML plays an important role in leukemogenesis, drug resistance and leukemia relapse.
Fu Li, Jiao Cai, Jiao Cai, Jia Liu, Shi-cang Yu, Xi Zhang, Yi Su, Lei Gao   +7 more
doaj   +1 more source

A Novel Predictor Tool of Biochemical Recurrence after Radical Prostatectomy Based on a Five-MicroRNA Tissue Signature [PDF]

, 2019
Within five to ten years after radical prostatectomy (RP), approximately 15-34% of prostate cancer (PCa) patients experience biochemical recurrence (BCR), which is defined as recurrence of serum levels of prostate-specific antigen >0.2 µg/L, indicating ...
Erbersdobler, Andreas, Fendler, Annika, Jung, Klaus, Jung, Monika, Kilic, Ergin, Lein, Michael, Stephan, Carsten, Weickmann, Sabine, Zhao, Zhongwei   +8 more
core   +2 more sources

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Prognostic value assessment and in vitro validation of mitochondria-ferroptosis-related genes in multiple myeloma

Scientific Reports
Multiple myeloma (MM) is a malignant plasma cell tumor. Mitochondria-related genes (MRGs) are significant inducers of ferroptosis. However, research on the involvement of mitochondria-ferroptosis-related genes (MFRGs) in the MM is relatively scarce, and ...
Jing Wu, Chen Li, Jiayou Zhang, Jing Su, Yuting Xiao, Linhua Ji   +5 more
doaj   +1 more source

Identification and validation of mRNA profiles linked to ATP- induced cell death represent a novel prognostic model for breast cancer

Frontiers in Immunology
BackgroundCell death mechanisms are integral to the pathogenesis of breast cancer (BC), with ATP-induced cell death (AICD) attracting increasing attention due to its distinctive specificity and potential therapeutic applications.MethodsThis study ...
Zhongwen Zhang, Haolong Zhang, Zheng Zhang, Doblin Sandai, Ping Lu, Haoling Zhang, Haoling Zhang, Haoling Zhang, Jianjun Wu   +8 more
doaj   +1 more source

Probabilistic Monte-Carlo method for modelling and prediction of electronics component life [PDF]

, 2014
Power electronics are widely used in electric vehicles, railway locomotive and new generation aircrafts. Reliability of these components directly affect the reliability and performance of these vehicular platforms.
Alghassi, Ali, Perinpanayagam, Suresh, Sreenuch, T., Xie, Ye   +3 more
core   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Analysis of the predictive postoperative recurrence performance of three lymph node staging systems in patients with colon cancer

Frontiers in Oncology
BackgroundColon cancer remains a major cause of cancer-related deaths worldwide, with recurrence post-surgery, posing a significant challenge. Accurate lymph node (LN) staging is critical for prognosis and treatment decisions, but traditional systems ...
Ning Meng, Zhiqiang Wang, Yaqi Peng, Xiaoyan Wang, Wenju Yue, Le Wang, Wenqian Ma   +6 more
doaj   +1 more source