Results 101 to 110 of about 842,511 (301)

OPTimal IMAging strategy in patients suspected of non-traumatic pulmonary disease at the emergency department: chest X-ray or ultra-low-dose CT (OPTIMACT)—a randomised controlled trial chest X-ray or ultra-low-dose CT at the ED: design and rationale

Diagnostic and Prognostic Research, 2018
Background Chest X-ray has been the standard imaging method for patients suspected of non-traumatic pulmonary disease at the emergency department (ED) for years. Recently, ultra-low-dose chest computed tomography (ULD chest CT) has been introduced, which
Inge A. H. van den Berk, Maadrika M. N. P. Kanglie, Tjitske S. R. van Engelen, Shandra Bipat, Marcel G. W. Dijkgraaf, Patrick M. M. Bossuyt, Wouter de Monyé, Jan M. Prins, Jaap Stoker   +8 more
doaj   +1 more source

Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery [PDF]

, 2009
: Objective To determine the effectiveness and cost effectiveness of using information from circulating biomarkers to inform the prioritisation process of patients with stable angina awaiting coronary artery bypass graft surgery.
Hemingway, Harry,, Hemingway, Harry, Sculpher, Mark,, Timmis, Adam,, Sculpher, Mark, Abrams, Keith,, Henriksson, M, K Fitzpatrick, Natalie,, Hingorani, Aroon D,, Chen, R, Kaski, Juan-Carlos,, Stenestrand, Ulf, Stenestrand, Ulf,, Hingorani, AD, Feder, G, Henriksson, Martin,, Janzon, M, Janzon, Magnus, Fitzpatrick, NK, Abrams, K, Damant, Jacqueline, Feder, Gene,, Palmer, S, Damant, Jacqueline,, Shipley, MJ, Chen, Ruoling, Timmis, A, K Fitzpatrick, Natalie, Abrams, Keith, Sculpher, M, Palmer, Stephen, Stenestrand, U, Keogh, B, Janzon, Magnus,, Damant, J, Feder, Gene, Shipley, Martin J, Henriksson, Martin, Kaski, JC, Hingorani, Aroon D, Keogh, Bruce, Keogh, Bruce,, Hemingway, H, Timmis, Adam, Fitzpatrick, Natalie K, Shipley, Martin J,, Kaski, Juan-Carlos   +46 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hot spots and trends in PCI prognostic research: A bibliometric analysis with CiteSpace. [PDF]

Medicine (Baltimore), 2023
Guo S, Luo X, Huang L, Wang C, Yang Y, Yang L.   +5 more
europepmc   +1 more source

Prognosis of patients with hepatocellular carcinoma. Validation and ranking of established staging-systems in a large western HCC-cohort. [PDF]

, 2012
HCC is diagnosed in approximately half a million people per year, worldwide. Staging is a more complex issue than in most other cancer entities and, mainly due to unique geographic characteristics of the disease, no universally accepted staging system ...
Straub, Gundula, Rolf Lamerz (128813), Göke, Burkhard, Christoph J Zech, Thomas Nickel (128829), Markus Rentsch (128832), Frank T Kolligs, Dorothea Nagel, Christoph J. Zech (128818), Sappl, Julia, Markus Rentsch, Burkhard Göke (109829), Mark op den Winkel, Petra Stieber (65225), Nagel, Dorothea, Petra Stieber, Burkhard Göke, Thomas Nickel, Mark op den Winkel (128802), Dorothea Nagel (65229), Gundula Straub, Lamerz, Rolf, Julia Sappl, Stieber, Petra, Kolligs, Frank T., Rentsch, Markus, Rolf Lamerz, Nickel, Thomas, Winkel, Philip op den, Julia Sappl (128805), Frank T. Kolligs (128835), Philip op den Winkel, Philip op den Winkel (128808), Gundula Straub (128821), Winkel, Mark op den, Zech, Christoph J.   +35 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Commentary: The Circulatory Effects of Increased Hydrostatic Pressure Due to Immersion and Submersion

Frontiers in Physiology, 2022
Jacques Regnard, Malika Bouhaddi, Olivier Castagna, Olivier Castagna, Laurent Mourot, Laurent Mourot   +5 more
doaj   +1 more source

Editorial: Prognostic research and precision oncology in upper tract urothelial carcinoma-volume II. [PDF]

Front Oncol, 2023
Yang TM, Singla N, Chen CH, Hsieh JT, Yeh HC.   +4 more
europepmc   +1 more source

Patient-specific data fusion defines prognostic cancer subtypes [PDF]

, 2011
Different data types can offer complementary perspectives on the same biological phenomenon. In cancer studies, for example, data on copy number alterations indicate losses and amplifications of genomic regions in tumours, while transcriptomic data ...
Richard S. Savage, Yuan Yinyin, Yuan, Yinyin, Markowetz, Florian, Richard S Savage, Florian Markowetz, Savage Richard S., Savage, Richard S., Markowetz Florian, Yinyin Yuan   +9 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source