Results 111 to 120 of about 842,511 (301)

Risk prediction tools for pressure injury occurrence: an umbrella review of systematic reviews reporting model development and validation methods

Diagnostic and Prognostic Research
Background Pressure injuries (PIs) place a substantial burden on healthcare systems worldwide. Risk stratification of those who are at risk of developing PIs allows preventive interventions to be focused on patients who are at the highest risk.
Bethany Hillier, Katie Scandrett, April Coombe, Tina Hernandez-Boussard, Ewout Steyerberg, Yemisi Takwoingi, Vladica Velickovic, Jacqueline Dinnes   +7 more
doaj   +1 more source

Developing a Core Outcome Set for Prognostic Research in Palliative Cancer Care: Protocol for a Mixed Methods Study. [PDF]

JMIR Res Protoc, 2023
Spooner C, Vivat B, White N, Stone P.
europepmc   +1 more source

Prognostic factors for malignant mesothelioma in 142 patients : validation of CALGB and EORTC prognostic scoring systems

, 2000
*This article is free to read on the publisher's website*\ud \ud Background \ud \ud The incidence of malignant mesothelioma is increasing. There is the perception that survival is worse in the UK than in other countries.
Leverment, JN., O'Byrne, K.J., Waller, D.A., Abrams, K.R., Edwards, J.G., Spyt, T.J.   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Expert panel as reference standard procedure in diagnostic accuracy studies: a systematic scoping review and methodological guidance

Diagnostic and Prognostic Research
Background In diagnostic accuracy studies, when no reference standard test is available, a group of experts, combined in an expert panel, is often used to assess the presence of the target condition using multiple relevant pieces of patient information ...
Bas E. Kellerhuis, Kevin Jenniskens, Mike P. T. Kusters, Ewoud Schuit, Lotty Hooft, Karel G. M. Moons, Johannes B. Reitsma   +6 more
doaj   +1 more source

Editorial: Prognostic Research and Precision Oncology in Upper Tract Urothelial Carcinoma. [PDF]

Front Oncol, 2022
Sheu ZL, Singla N, Chen CH, Hsieh JT, Yeh HC.   +4 more
europepmc   +1 more source

Study of prognostic markers in advanced cancer [PDF]

, 2019
BACKGROUND: Prognostication is a core skill fundamental to the clinical management of patients with advanced cancer. This skill is exercised to guide appropriate clinical decisions, plan supportive services and allocate resource utilisation ...
Simmons, Claribel Patrice Louise
core  

Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints [PDF]

, 2011
Recent advances in cardiovascular magnetic resonance (CMR) now allow the accurate and reproducible measurement of many aspects of cardiac and vascular structure and function, with prognostic data emerging for several key imaging biomarkers.
Pitcher, A, D. Ashby, S. E. Petersen, Petersen, SE, Elliott, P, P. Elliott, A. Pitcher, Ashby, D   +7 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The development and internal validation of a multivariable model predicting 6-month mortality for people with opioid use disorder presenting to community drug services in England: a protocol

Diagnostic and Prognostic Research
Background People with opioid use disorder have substantially higher standardised mortality rates compared to the general population; however, lack of clear individual prognostic information presents challenges to prioritise or target interventions ...
Emmert Roberts, John Strang, Patrick Horgan, Brian Eastwood   +3 more
doaj   +1 more source