Results 101 to 110 of about 7,909 (155)

A novel gross deletion in the progranulin gene in four subjects with frontotemporal dementia. [PDF]

Neurol Sci
Ricci M, Di Fede G, Caroppo P, Aprea V, Villa C, Romeo A, Tiraboschi P, Marti A, Grisoli M, Piccione MM, Cimini S, Rossi G.   +11 more
europepmc   +1 more source

Synergistic cooperation between progranulin and Jak2/Stat3 signaling determines definitive myeloid cell fate. [PDF]

Cell Rep
McCune A, Usha MK, Baldus I, Willett CJ, Ferrito N, Barakat R, Clemensen E, Snella E, Morton M, Lacal J, Pavani G, Campbell CA, Espin-Palazon R.   +12 more
europepmc   +1 more source

Expression of progranulin (GP88) protein appears as an independent prognostic factor for clinical progression in high-risk prostate cancer patients. [PDF]

Sci Rep
Dubrovska R, Eckstein M, Jung R, Kalogirou C, Kneitz B, Spahn M, Kruithof-de Julio M, Serrero G, Yue B, Geppert C, Stöhr R, Hartmann A, Wullich B, Lieb V, Taubert H, Wach S.   +15 more
europepmc   +1 more source

Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration. [PDF]

iScience
Sajan MP, Aggarwal G, Hwang JJ, Smith DM, Cooper DR, Duncan MA, Hansen BC, Nguyen AD, Farese RV.   +8 more
europepmc   +1 more source

Progranulin genetic variant rs5848 displays ancestry-specific associations with Alzheimer's disease. [PDF]

Hum Genomics
Life BE, Navarro-Delgado EI, Fornes O, Friedman JM, Wasserman WW, Korthauer K, Leavitt BR.   +6 more
europepmc   +1 more source

The highest clinical trial failure rate for any disease in modern medicine: How both amyloid- and non-amyloid-targeting therapies failed to alter disease course in Alzheimer's disease. [PDF]

Free Neuropathol
Guth MAS.
europepmc   +1 more source

Progranulin Is a Useful Biomarker to Predict Mortality in ICU Patients with Low Burden of Organ Dysfunction. [PDF]

Biomedicines
Schoettler JJ, Pridzun L, Flehmig B, Lindner HA, Schneider-Lindner V, Krebs J, Centner FS, Thiel M.   +7 more
europepmc   +1 more source

Progranulin Is a Survival Factor for Axotomized Retinal Ganglion Cells in Adult Mice. [PDF]

Cells
Grodzki LM, Schlichting S, Hu Y, Helbing S, Bartsch U.   +4 more
europepmc   +1 more source

Are Signal Peptides Hidden Regulators of Neurodegenerative Disease? [PDF]

Biomedicines
Karbownik M, Fidura M, Perlikowska R.
europepmc   +1 more source

Progranulin deficiency induces premature vascular senescence and dysfunction. [PDF]

Am J Physiol Heart Circ Physiol
Luvizotto RAM, Nascimento AF, Pimenta GF, de Costa RM, Beling T, Singh S, Alves JV, Awata WMC, Russ A, Haastrup AI, Cuevas RA, Behzadi P, St Hilaire C, Roberts JT, Bruder A, Bruder-Nascimento T.   +15 more
europepmc   +1 more source