Results 21 to 30 of about 20,462 (241)

Progressive multifocal leukoencephalopathy [PDF]

Current Neurology and Neuroscience Reports, 2000
Progressive multifocal leukoencephalopathy (PML) was a rare disease until the advent of the HIV/AIDS pandemic. Recent interest in the disorder has been spurred by its appearance in patients treated with the monoclonal antibodies natalizumab and rituximab.
openaire   +5 more sources

A programme for risk assessment and minimisation of progressive multifocal leukoencephalopathy developed for vedolizumab clinical trials [PDF]

, 2018
Introduction Over the past decade, the potential for drug-associated progressive multifocal leukoencephalopathy (PML) has become an increasingly important consideration in certain drug development programmes, particularly those of immunomodulatory ...
Berger, Joseph R, Clifford, David B, Fox, Irving, Lev, Michael H, Major, Eugene, McAuliffe, Megan, Milch, Catherine, Parikh, Asit, Patti, Mark, Provenzale, James M, Sankoh, Serap, Shick, Jesse, Stephens, Kristin   +12 more
core   +3 more sources

Asymptomatic progressive multifocal leukoencephalopathy: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background We report the development of asymptomatic progressive multifocal leukoencephalopathy in a patient with multiple sclerosis on natalizumab therapy.
Yinan Zhang, Crystal Wright, Angela Flores   +2 more
doaj   +1 more source

Cerebral lesions in hematological malignancies: a case report

Journal of Medical Case Reports, 2021
Background Progressive multifocal leukoencephalopathy is a rare central nervous system disease, resulting from reactivation of latent John Cunningham virus.
Nicoletta D’Ettore, Valentina Scheggi, Brunetto Alterini, Niccolò Marchionni   +3 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy [PDF]

Neurology, 2002
A 58-year-old woman admitted to the hospital had a 3-month history of progressive neurologic deterioration characterized by severe global aphasia and bilateral limb weakness, greater on the right. The patient had a 10-year history of systemic lupus erythematosus (SLE). Polyarthritis had been present for 6 weeks before the …
Henderson, R. D., Smith, M. G., Mowat, P., Read, S. J.   +3 more
openaire   +2 more sources

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy [PDF]

, 2006
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had developed in any other treated patients.
Barkhof, F., Clifford, D.B., Curfman, B., Fahle, G., Fischer, S., Habil, M., Hou, J., Jäger, H.R., Major, E.O., Miszkiel, K., Mueller-Lenke, N., Radue, E.-W., Ryschkewitsch, C., Sanchez, E., Yousry, T.A.   +14 more
core   +1 more source

Progressive multifocal leukoencephalopathy triggered by COVID-19 in a previously asymptomatic person living with undiagnosed HIV infection

International Journal of Infectious Diseases, 2023
This report presents the case of a 47-year-old male patient who worked as a mathematics teacher and experienced the sudden onset of disorientation, aphasia, and acalculia during an online class.
Yago Marcos Pessoa-Gonçalves, Thaís Soares Farnesi-de-Assunção, Marlos Aureliano Dias de Sousa, Luis Marcos Ferreira, Junior, Beatriz Sodré Matos, Anna Victória Bernardes Borges, Ana Carolina de Morais Oliveira-Scussel, Alex Eduardo da Silva, Carlo José Freire Oliveira, Marcos Vinicius da Silva, Virmondes Rodrigues, Junior   +10 more
doaj   +1 more source

Acquired immunodeficiency syndrome-related progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome: prevalence, main characteristics, and outcomes in a Brazilian center

Arquivos de Neuro-Psiquiatria, 2023
Background Progressive multifocal leukoencephalopathy (PML) - immune reconstitution inflammatory syndrome (IRIS) in people living with HIV/AIDS (PLWHA) has been rarely described in low- and middle-income countries.
Monize Nascimento Santana, Raphaela Ferrari, Arthur Cassa Macedo, Rosa Maria Nascimento Marcusso, Ruan de Andrade Fernandes, José Ernesto Vidal   +5 more
doaj   +1 more source

EFFICIENT PROPAGATION OF ARCHETYPE JC POLYOMAVIRUS IN COS-7 CELLS: EVALUATION OF REARRANGEMENTS WITHIN NCCR STRUCTURAL ORGANIZATION DURING TRANSFECTION. [PDF]

, 2017
John Cunningham virus (JCPyV) is an ubiqui-tous human pathogen that causes disease in immunocom-promised patients. The JCPyV genome is composed of an early region and a late region, which are physically sepa-rated by the ...
Anzivino, Elena, Bellizzi, Anna, Palamara, ANNA TERESA, Pietropaolo, Valeria Antonietta, Prezioso, Carla, Rodio, DONATELLA MARIA, Scribano, D, Trancassini, Maria   +7 more
core   +1 more source

Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab

Emerging Infectious Diseases, 2018
Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore ...
Martin Martinot, Guido Ahle, Inesa Petrosyan, Camille Martinez, Dragos M. Gorun, Mahsa Mohseni-Zadeh, Samira Fafi-Kremer, Martine Tebacher-Alt   +7 more
doaj   +1 more source