AIDS-related progressive multifocal leukoencephalopathy
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão+5 more
doaj +1 more source
Atezolizumab Treatment for Progressive Multifocal Leukoencephalopathy
Atezolizumab successfully reinvigorated JC virus immunity in a patient in Belgium with progressive multifocal leukoencephalopathy, as demonstrated by clinical, virologic, and radiologic response to treatment.
Nicolas Lambert+4 more
doaj +1 more source
Introduction: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection ...
Luís Augusto+4 more
doaj +1 more source
Case report of a patient with progressive multifocal leukoencephalopathy under treatment with dimethyl fumarate [PDF]
BACKGROUND: Progressive multifocal leukoencephalopathy is a severe demyelinating disease caused by the polyoma JC virus in patients with reduced immunocompetence.
Antje Bornemann+4 more
core +1 more source
Progressive multifocal leukoencephalopathy [PDF]
A 58-year-old woman admitted to the hospital had a 3-month history of progressive neurologic deterioration characterized by severe global aphasia and bilateral limb weakness, greater on the right. The patient had a 10-year history of systemic lupus erythematosus (SLE). Polyarthritis had been present for 6 weeks before the …
Henderson, R. D.+3 more
openaire +3 more sources
Cerebral lesions in hematological malignancies: a case report
Background Progressive multifocal leukoencephalopathy is a rare central nervous system disease, resulting from reactivation of latent John Cunningham virus.
Nicoletta D’Ettore+3 more
doaj +1 more source
HIV-associated progressive multifocal leukoencephalopathy. Current perspectives [PDF]
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, caused by the polyomavirus JC and occurring almost exclusively in the context of severe immune depression.
Ciardi, M. R.+6 more
core +1 more source
Asymptomatic progressive multifocal leukoencephalopathy: a case report and review of the literature
Background We report the development of asymptomatic progressive multifocal leukoencephalopathy in a patient with multiple sclerosis on natalizumab therapy.
Yinan Zhang+2 more
doaj +1 more source
A programme for risk assessment and minimisation of progressive multifocal leukoencephalopathy developed for vedolizumab clinical trials [PDF]
Introduction Over the past decade, the potential for drug-associated progressive multifocal leukoencephalopathy (PML) has become an increasingly important consideration in certain drug development programmes, particularly those of immunomodulatory ...
Berger, Joseph R+12 more
core +3 more sources
The still under-investigated role of cognitive deficits in PML diagnosis [PDF]
Background: Despite cognitive deficits frequently represent the first clinical manifestations of Progressive Multifocal Leukoencephalopathy (PML) in Natalizumab-treated MS patients, the importance of cognitive deficits in PML diagnosis is still under ...
Amato, Maria Pia+49 more
core +2 more sources