Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the central nervous system (CNS) caused by the reactivation of John Cunningham polyomavirus (JCV).
Yancheva-Petrova N. +6 more
doaj +1 more source
Concomitant granule cell neuronopathy in patients with natalizumab-associated PML [PDF]
Granule cell neuronopathy (GCN) is a rare JC virus infection of the cerebellar granule cell neurons in immunocompromised patients. On brain imaging, GCN is characterized by cerebellar atrophy which can be accompanied by infratentorial white matter ...
Eijk, J.J.J. (Jeroen) van +4 more
core +1 more source
JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient
Background JC virus (JCV) is common among healthy individuals and remains latent but may be reactivated under immunosuppressive conditions, resulting in progressive multifocal leukoencephalopathy (PML).
Xiang Wang +4 more
doaj +1 more source
Myoclonus as an unusual presentation of progressive multifocal leukoencephalopathy in a HIV positive patient [PDF]
From mild muscular contractions to gross jerks affecting the whole body, myoclonus is an involuntary movement caused by an excessive discharge from a group of neurons located in one or multiple sites from cortical to peripheral level.
Lucian Chicea +4 more
doaj +1 more source
Rituximab-Associated Inflammatory Progressive Multifocal Leukoencephalopathy
Progressive multifocal leukoencephalopathy (PML) is a rare disease of the immunosuppression that results from neurotropic invasion of the JC virus which leads to demyelination of oligodendrocytes.
Chandra Punch +2 more
doaj +1 more source
Progressive Multifocal Leukoencephalopathy in an AIDS Patient
Progressive multifocal leukoencephalopathy (PML) is a demyelinating brain disease caused by Jamestown Canyon virus (JCV). This disease is an important cause of morbidity and mortality in acquired immunodeficiency syndrome (AIDS) patients.
Ming-Hsing Lee +2 more
doaj +1 more source
Does Mefloquine (Lariam®) Therapy Improve the Prognosis of Human JC Polyomavirus-Induced Progressive Multifocal Leukoencephalopathy? [PDF]
Progressive multifocal leukoencephalopathy (PML) is ademyelinating disease caused by infection with Polyomavirus hominis 2, popularly known as JC virus (JCV).
Zlatko Kalvatchev, Iliya Tsekov
doaj +3 more sources
Brain abscess following rituximab infusion in a patient with pemphigus vulgaris. [PDF]
BackgroundImmunocompromised patients are at increased risk for developing meningitis or, rarely, brain abscess with opportunistic organisms like Listeria monocytogenes.Case reportA 52 year-old Saudi Arabian woman who was diagnosed with pemphigus vulgaris
Al-Harbi, Talal M +2 more
core +2 more sources
Stratification and monitoring of natalizumab-associated progressive multifocal leukoencephalopathy risk: recommendations from an expert group [PDF]
The use of natalizumab for highly active relapsing-remitting multiple sclerosis (MS) is influenced by the occurrence of progressive multifocal leukoencephalopathy (PML).
Craner, M +10 more
core +1 more source
Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville +6 more
wiley +1 more source

