Progressive Multifocal Leukoencephalopathy in an AIDS Patient
Journal of the Formosan Medical Association, 2007 Progressive multifocal leukoencephalopathy (PML) is a demyelinating brain disease caused by Jamestown Canyon virus (JCV). This disease is an important cause of morbidity and mortality in acquired immunodeficiency syndrome (AIDS) patients.
Ming-Hsing Lee +2 more
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EFFICIENT PROPAGATION OF ARCHETYPE JC POLYOMAVIRUS IN COS-7 CELLS: EVALUATION OF REARRANGEMENTS WITHIN NCCR STRUCTURAL ORGANIZATION DURING TRANSFECTION. [PDF]
, 2017 John Cunningham virus (JCPyV) is an ubiqui-tous human pathogen that causes disease in immunocom-promised patients. The JCPyV genome is composed of an early region and a late region, which are physically sepa-rated by the ...
Anzivino, Elena +7 more
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Progressive multifocal leukoencephalopathy (PML) after transplantation [PDF]
Pediatric Transplantation, 2011 Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal opportunistic demyelinating disorder related to a viral infection of the central nervous system that was initially described in immunocompromised patients. It has commonly been reported in patients with hematologic malignancies, systemic lupus erythematosus, and chronic ...
Christina, Nguyen, Ron, Shapiro
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A case of progressive multifocal leukoencephalopathy in a HIV-infected female patient [PDF]
Терапевтический архив, 2016 Progressive multifocal leukoencephalopathy (PML) caused by JC virus is a severe central nervous lesion developing in the presence of obvious immunodeficiency. In most cases, the disease results in a fatal outcome within a few months.
E A Samotolkina +4 more
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JC virus-DNA detection is associated with CD8 fffector accumulation in peripheral blood of patients with multiple sclerosis under natalizumab treatment, independently from JC virus serostatus [PDF]
, 2018 Although natalizumab (anti-α4 integrin) represents an effective therapy for relapsing remitting multiple sclerosis (RRMS), it is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), caused by the polyomavirus ...
Anzivino, Elena +16 more
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Journal of Family Medicine and Primary Care, 2019 We describe the case of an HIV/AIDS patient with progressive multifocal leukoencephalopathy (PML) associated with immune reconstitution inflammatory syndrome (IRIS) and the diagnostic and management dilemmas in distinguishing between PML and PML-IRIS ...
Rahul R Abraham +4 more
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Emerging Infectious Diseases, 2019 Antibodies against PD1 have been used to treat progressive multifocal leukoencephalopathy (PML), a rare brain disease caused by JC virus. We used these antibodies (nivolumab) to treat PML in 3 kidney transplant recipients.
Chloé Medrano +5 more
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eJHaem, 2020 Progressive multifocal leukoencephalopathy (PML) may develop in follicular lymphoma patients treated with bendamustine‐rituximab. In this report, treatment with pembrolizumab successfully inhibited the clinical progression of PML by promoting ...
Inès Dufour +7 more
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Progressive Multifocal Leukoencephalopathy in an Immunocompetent Patient
Case Reports in Neurology, 2013 Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients.
Krisztina K. Johansen +3 more
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Immunological biomarkers identifying natalizumab-treated multiple sclerosis patients at risk of progressive multifocal leukoencephalopathy [PDF]
, 2014 Natalizumab-induced progressive multifocal leukoencephalopathy (PML) appears to be unleashed by complex interactions between viral and immunological host factors leading the latent form of JC virus to become pathogenic.
A.SOTTINI +8 more
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