Results 81 to 90 of about 5,411,820 (260)
Understanding progression in primary progressive multiple sclerosis: a longitudinal clinical and magnetic resonance imaging study [PDF]
, 2010 The work in this thesis applies magnetization transfer imaging (MTI) and conventional MRI measures (brain volume, T2 lesion load and enhancing lesions) to investigate the mechanisms underlying progression in primary progressive multiple sclerosis ...
Khaleeli, Z.
core
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Progressive Dwindling in Multiple Sclerosis: An Opportunity to Improve Care [PDF]
, 2016 Introduction In the general ageing population, 40% of deaths occur following a prolonged trajectory of “progressive dwindling,” characterised by chronic accumulation of disability and frailty, and associated with increased dependency and reduced ...
Martin, J +5 more
core +1 more source
OCRELIZUMAB IN THE TREATMENT OF PRIMARY-PROGRESSIVE MULTIPLE SCLEROSIS
Медицинский совет, 2018 This article presents the review of results of clinical trials of drugs for pathogenetic therapy of primary progressive multiple sclerosis, including ocrelizumab.
E. V. Popova
doaj +1 more source
Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis [PDF]
, 2010 Cerebral atrophy is a correlate of clinical progression in multiple sclerosis (MS). Mitochondria are now established to play a part in the pathogenesis of MS.
Turnbull, Doug M +18 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Recent developments in multiple sclerosis therapeutics
BMC Medicine, 2009 Multiple sclerosis, the most common neurologic disorder of young adults, is traditionally considered to be an inflammatory, autoimmune, demyelinating disease of the central nervous system.
Bourdette Dennis +2 more
doaj +1 more source
Migration and infectious disease in the etiology of multiple sclerosis: A case-control study
, 1989 Epidemiological study on multiple sclerosis risk of migration from South to North ...
Altobelli A. +2 more
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A grounded theory analysis of the occupational impact of caring for a partner who has multiple sclerosis [PDF]
, 2006 Chronic progressive conditions such as multiple sclerosis impact engagement in and orchestration of daily occupations by people with the condition, and their family members.
Molineaux, M +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source