Results 61 to 70 of about 114,951 (282)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Delegation, Knowledge Integration, and Cooperation: How to Solve Problems of Coordination in Structural Fund Programs. Findings From Comparative Case Studies in the South of Italy [PDF]

European cohesion policies are increasingly relying on grassroots networks tapping into tacit knowledge and participatory decision-making processes. Regional governments delegate their decision making power to local institutions with the assumption that ...
Mita Marra
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Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Recreation Programming Study: Prepared for the Town-School Coordination Committee

, 2010
The Town of Ipswich, acting for its Town-School Coordination Committee (the Committee) contracted with the Edward J. Collins, Jr. Center for Public Management at the University of Massachusetts Boston to conduct a preliminary assessment of the current ...
Edward J. Collins, Jr. Center for Public Management, University of Massachusetts Boston
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Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream

BMJ Open
Introduction Children represent a large and vulnerable patient group. However, the evidence base for most paediatric diagnostic and therapeutic procedures remains limited or is often inferred from adults.
, Julia A Bielicki, Luregn J Schlapbach, Klara Posfay-Barbe, Sven Schulzke, Martin Stocker, Anita Rauch, Christopher B Forrest, Effy Vayena, Claudia E Kuehni, Jacques Fellay, Philipp Latzin, Christian Kahlert, Seraina Prader, Ben D Spycher, Katrin Männik, Jana Pachlopnik Schmid, Klara M Posfay-Barbe, Roger Lauener, Keith Harshman, Kelly Ormond, Manon Jaboyedoff, Eric Giannoni, Tatjana Welzel, Dylan Lawless, Rebeca Mozun, Fabiën N Belle, Andrea Agostini, Matthias R Baumgartner, D Sean Froese, Sandra Goetze, Kathrin Hofmann, Aurélie Martin Necker, Patrick G A Pedrioli, Sven M Schulzke, Nicola Zamboni, Julia E Vogt, Audrey van Drogen, Aurélie Martin Necker, Cornelia Hagman, D Sean Froese, Daphné Chopard, Eirini I Petrou, Emanuele Palumbo, Ioannis Xenarios, Jana Pachlopnik Schmid, Léa Ho Dac, Lorenz M Leuenberger, Mariam Ait Oumelloul, Nicole Goebel, Simon Boutry, Thomas M Sutter, Varvara Dimopoulou, Vito RT Zanotelli, Xeni Deligianni, Xenia Bovermann, Yara Shoman, Anna Hartung   +57 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Design chain management : inter-organisational coordination of product development in the UK automotive industry [PDF]

This thesis examines the inter-firm management of product development between a vehicle manufacturer and six component suppliers actively participating in the design and development process.
Twigg, David
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AIDS, drought, and child malnutrition in southern Africa. [PDF]

, 2005
OBJECTIVE: To investigate trends in child malnutrition in six countries in southern Africa, in relation to the HIV epidemic and drought in crop years 2001/2 and 2002/3.
Mason, Karen E, Kendle, Andrea, Pierre Martel, Dominique Brunet, Andrea Kendle, Hailey, Peter, Martel, Pierre, John B Mason, Hudspeth, Claudia, Karen E Mason, Jonsson, Urban, Olivia Yambi, Peter Hailey, Brunet, Dominique, Yambi, Olivia, Mason, John B, Bailes, Adam, Adam Bailes, Claudia Hudspeth, Urban Jonsson   +19 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Company Taxes in the European Union: Criteria and Options for Reform [PDF]

In 1992, the Ruding Committee, appointed by the European Commission to examine the need for company tax (CT) harmonisation in the European Union (EU), presented its findings and recommendations.2 Although the Committee concluded that differences in CTs ...
Sijbren Cnossen
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