Results 111 to 120 of about 9,735,717 (300)

Governance, governmentality and project performance: the role of sovereignty

International Journal of Information Systems and Project Management, 2019
Considerable confusion prevails in the mutual positioning and relationship of concepts like management, leadership, governance and governmentality in projects.
Ralf Müller, , , ,
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Governance and returns on investment : an empirical investigation [PDF]

Using data from the World Bank's Operations Evaluation Department, the authors examine the link between the performance of Bank-financed projects and various indicators of country governance.
Isham, Jonathan, Pritchett, Lant, Kaufmann, Daniel   +2 more
core  

Governing and (re)producing project governance [PDF]

, 2019
Public-Private Partnerships (PPPs) are usually presented as collaborative inter-organizational relationships between public and private organizations for increasing the efficiency of public infrastructure delivery. Yet, PPPs are realized in very particular long-term contractual engagements, whose effects on the quality of the partnership and its ...
openaire   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Optimizing Engineering Project Governance for Sustainability [PDF]

, 2011
Organisations are increasingly leveraging improved decision making processes during the establishment of project teams. Beyond the obvious advantages of accessing qualified, cost-effective project staff, the issues of sustainability and governance are ...
Luke Houghton, Houghton, Luke, Yuk Kuen Wong, Tuffley, David, David Tuffley, Wong, Yuk Kuen   +5 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Readiness-Gate Governance in Public Infrastructure Projects Preventing Premature Milestones, Infrastructure Gridlocks and Trust Loss

Journal of Asia Entrepreneurship and Sustainability
Public infrastructure projects often lose time and trust not simply because engineering work is difficult, but because leaders commit to milestones before the conditions required for those milestones are mature.
Dr. Alok Kumar Bhargava, Dr. Sonali Sneha   +1 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source