Results 71 to 80 of about 2,155,686 (262)

Climate change and natural hazards in the Alps

open access: yesRevue de Géographie Alpine, 2015
Under the effects of climate change, Alpine mountainous regions are undergoing fast and well-perceptible evolutions, which are attracting the growing attention of people, scientists and managers.
Benjamin Einhorn   +10 more
doaj   +1 more source

COSMO-CLM Performance and Projection of Daily and Hourly Temperatures Reaching 50 °C or Higher in Southern Iraq

open access: yesAtmosphere, 2020
Fortunately, extreme temperatures reaching 50 °C are not common on our planet. The capability of the consortium for small-scale modelling regional climate model (COSMO-CLM), with 0.44° resolution, to project future trends of an extremely hot environment ...
Yoav Levi, Yossi Mann
doaj   +1 more source

Projects and Projections

open access: yesPolitical Theory, 2001
This is a preprint (author's original) version of the article published in Political Theory 29(1):86-90. The final version of the article can be found at http://www.jstor.org/stable/3072545 (login required to access content). The version made available in Digital Common was supplied by the author.
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

“Here, I am More than Just Symptoms Combined”: Mental Health Services from the Perspective of Community Rehabilitation Groups

open access: yesJournal of Patient Experience
In response to the rise in mental disorders, psychosocial and community approaches have been proposed, complementing traditional clinical services.
Felipe Agudelo Hernández PhD, MD   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

PROFESSIONAL STANDARDS AND THEIR ROLE AT PROJECTION OF BASIC EDUCATIONAL PROGRAMS OF TEACHERS’ PREPARATION

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2017
New notions of professional standard are revealed. They are classification of a worker, generalized work functions, work functions. The normative-legal basis is considered. Professional standards were created on its basis.
N. E. Kopytova, L. N. Makarova
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Pancreatic cancer mortality trends attributable to high fasting blood sugar over the period 1990–2019 and projections up to 2040

open access: yesFrontiers in Endocrinology
BackgroundPancreatic cancer (PC) is a prevalent malignancy within the digestive system, with diabetes recognized as one of its well-established risk factors.MethodsData on PC mortality attributed to high fasting blood sugar were retrieved from the Global
Yongguang Wei   +27 more
doaj   +1 more source

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