Results 71 to 80 of about 148,159 (238)
Projection Pursuit for Exploratory Supervised Classification [PDF]
In high-dimensional data, one often seeks a few interesting low-dimensional projections that reveal important features of the data. Projection pursuit is a procedure for searching high-dimensional data for interesting low-dimensional projections via the ...
Dianne Cook +3 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Determining the number of clusters using nonparametric statistics
Lietuvos Matematikos Rinkinys, 1997 A Gaussian mixture model is investigated in this paper. A method for estimation of unknown number of clusters in the case of equal covariance matrices is discribed. This method is based on the use of projection pursuit.
Darius Šimoliūnas
doaj +1 more source
Latent Factor Prediction Pursuit for Rank Deficient Regressors [PDF]
In simulation studies Latent Factor Prediction Pursuit outperformed classical reduced rank regression methods. The algorithm described so far for Latent Factor Prediction Pursuit had two shortcomings: It was only implemented for situations where the ...
Czogiel, Irina +2 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Data processing method for telecom data based on projection pursuit
Dianxin kexue, 2016 In the big data era, the data which operator can collect and process is quickly growing. At the same time, due to the high dimension of the data, it is very difficult to extract and process information from them.
Jinming ZHAO
doaj +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Two Dimensional Projection Pursuit Applied to Gaussian Mixture Model Fitting [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 In this paper we seek a Gaussian mixture model (GMM) of an n-variate probability density function. Usually the parameters of GMMs are determined by a maximum likelihood (ML) criterion. A practical deficiency of ML fitting of GMMs is poor performance when
Natella Likhterov, Mayer Aladjem
doaj
High breakdown estimators for principal components: the projection-pursuit approach revisited. [PDF]
Li and Chen (J. Amer. Statist. Assoc. 80 (1985) 759) proposed a method for principal components using projection-pursuit techniques. In classical principal components one searches for directions with maximal variance, and their approach consists of ...
Croux, Christophe, Ruiz-Gazen, A
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