Results 11 to 20 of about 4,973 (169)

Symptom Overlap Stratifies Prokinetic Response in Functional Dyspepsia: A Real‐World Multicenter Study of 1297 Chinese Patients [PDF]

JGH Open
Objective Functional dyspepsia (FD) often overlaps with GERD‐, IBS‐, and FC‐like symptoms, complicating treatment. This study evaluated overlap patterns and their association with cinitapride response in Chinese FD patients.
Dan Zhou, Tao Bai, Jie Chen, Doneke Wang, Jinsong Liu, Xiaohua Hou   +5 more
doaj   +2 more sources

Preferences on the Use of Prokinetic Agents in Adult Intensive Care Unit Patients-An International Survey. [PDF]

Acta Anaesthesiol Scand
Crone V, Møller MH, Alhazzani W, Grønningsæter L, Al-Fares A, Hästbacka J, Ostermann M, Pfortmueller CA, Ferrer R, Blaser AR, Sigurdsson MI, Wall O, Keus E, Szczeklik W, Young PJ, McGrath C, Cecconi M, Perner A, Krag M.   +18 more
europepmc   +2 more sources

Serious Adverse Events in Adult ICU Patients: A Substudy of the PATIENCE Cohort. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Introduction Prokinetic agents are used to enhance upper gastrointestinal motility, but adverse events related to these agents are poorly described. We aimed to provide detailed epidemiological data on predefined serious adverse events (SAEs) in a cohort of adult intensive care unit (ICU) patients with and without prokinetic treatment.
Crone V, Møller MH, Granholm A, Perner A, Alhazzani W, Al-Fares A, Hästbacka J, Ostermann M, Pfortmueller CA, Ferrer R, Blaser AR, Keus E, Szczeklik W, Krag M.   +13 more
europepmc   +2 more sources

Mosapride versus Metoclopramide in Critically Ill Patients with Enteral Feeding Intolerance: A Randomized, Double-Blinded Comparison [PDF]

Drug Design, Development and Therapy
Eman Mohamed Elmokadem,1,* Dina Khaled Abou El Fadl,1,* Ahmed M Bassiouny,2,3 Amir Eskander Hanna Samy,4 Nouran Omar El Said1,* 1Department of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmacy, Future University in ...
Mohamed Elmokadem E, Khaled Abou El Fadl D, Bassiouny AM, Hanna Samy AE, Omar El Said N   +4 more
doaj   +2 more sources

The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia

Journal of Pharmacological Sciences, 2021
Functional dyspepsia (FD) is thought to be mainly based on gastric motility dysfunction and chronic hypersensitivity, yet FD animal models has been reported a few.
Kazuki Hashimoto, Kimihito Tashima, Taku Imai, Kenjiro Matsumoto, Syunji Horie   +4 more
doaj   +1 more source

The experience of using serotonin adipate in intensive care unit for non-surgical patients with gastrointestinal dysfunction

Клинический разбор в общей медицине, 2023
Gastrointestinal dysfunction is a disorder often found in critically ill patients that leads to nutritional deficiency resulting in the increase of the number of adverse events during hospitalization, more frequent hospital readmissions and steady ...
Nikolai P. Krotenko, Marina S. Grinenko
doaj   +1 more source

Management of Ineffective Esophageal Hypomotility

Frontiers in Pharmacology, 2021
Esophageal hypomotility in general and especially ineffective esophageal motility according to the Chicago criteria of primary motility disorders of the esophagus, is one of the most frequently diagnosed motility disorders on high resolution manometry ...
Sawangpong Jandee, Sawangpong Jandee, Annelies Geeraerts, Hannelore Geysen, Nathalie Rommel, Nathalie Rommel, Jan Tack, Jan Tack, Tim Vanuytsel, Tim Vanuytsel   +9 more
doaj   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough. [PDF]

Laryngoscope
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Allen J, Esna C, Prigent C, Miles A.
europepmc   +2 more sources

Urinary Metabolomic Profiling after Administration of Corydalis Tuber and Pharbitis Seed Extract in Healthy Korean Volunteers

Pharmaceutics, 2021
Pharmacometabolomics is a useful tool to identify biomarkers that can assess and predict response after drug administration. The primary purpose of pharmacometabolomics is to better understand the mechanisms and pathways of a drug by searching endogenous
Hyeon-Cheol Jeong, Jung Eun Park, Yohan Seo, Min-Gul Kim, Kwang-Hee Shin   +4 more
doaj   +1 more source

A Two-Stage Bedside Intubation Method to Improve Success Rate of Post-pyloric Placement of Spiral Nasoenteric Tubes in Critically Ill Patients: A Multi-Center, Prospective Study

Frontiers in Medicine, 2022
BackgroundsProkinetic agents could improve the success rate of post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs), and bedside blind technique might apply as a rescue therapy subsequent to spontaneous transpyloric migration failure.
Jing Xu, Jing Xu, Jing Xu, Sinian Li, Xiangyin Chen, Bo Tan, Shenglong Chen, Bei Hu, Zhiqiang Nie, Heng Ye, Cheng Sun, Ruibin Chi, Chunbo Chen, Chunbo Chen, Chunbo Chen, Chunbo Chen   +15 more
doaj   +1 more source