Results 31 to 40 of about 107,531 (235)

Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype [PDF]

open access: yes, 2010
Background Recent studies have indicated the presence of multipotent mesenchymal stromal cells (MSCs) in human lung diseases. Excess airway smooth muscle, myofibroblasts and activated fibroblasts have each been noted in asthma, suggesting that ...
Adam M Goldsmith   +8 more
core   +6 more sources

Positron Emission Tomography Imaging in Clinical Trials for Parkinson's Disease: Applications of Metabolic Brain Network Approach

open access: yesMovement Disorders, EarlyView.
ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan   +4 more
wiley   +1 more source

Involvement of miR-106b in tumorigenic actions of both prolactin and estradiol. [PDF]

open access: yes, 2017
Prolactin promotes a variety of cancers by an array of different mechanisms. Here, we have investigated prolactin's inhibitory effect on expression of the cell cycle-regulating protein, p21.
Bustamante, Karissa   +3 more
core   +1 more source

Systematic review and meta‐analysis of COVID‐19 association with human semen quality: Changes in semen parameters pre‐ and post‐COVID

open access: yesUroPrecision, EarlyView.
Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit   +2 more
wiley   +1 more source

Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]

open access: yes, 1989
We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain   +19 more
core   +1 more source

Pituitary apoplexy is associated with concurrent or subsequent diagnosis of human immunodeficiency virus

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objective Pituitary apoplexy (PA) is a rare condition caused by hemorrhage or infarction of the pituitary gland with associated risk of cranial neuropathies, endocrinopathies, and even death. Human immunodeficiency virus (HIV) has been shown to have some association with pituitary apoplexy, however, large‐scale studies have not been performed.
Jennifer E. Douglas   +11 more
wiley   +1 more source

Tryptophan research in panic disorder. [PDF]

open access: yes, 2008
A considerable body of evidence suggests the involvement of serotonin neurotransmission in the pathogenesis of panic disorder. Research on pathways and functions of tryptophan, an essential amino acid converted into serotonin, may advance our ...
Maron, E, Nutt, DJ, Shlik, J
core   +5 more sources

Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open‐Label Single‐Arm Clinical Trial

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Telogen effluvium (TE) is an acute and diffuse hair loss due to an abnormal increase in telogen hair follicles in response to external or internal factors. Recently, TE attracts global interest as a major cause of hair loss as a sequela of COVID‐19.
Manabu Ohyama   +6 more
wiley   +1 more source

Harbingers of change: Towards a mechanistic understanding of anticipatory plasticity in animal systems

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Phenotypic plasticity is a strategy by which animals alter behaviour, morphology and/or physiology in response to cues of current conditions to cope with environmental heterogeneity.
Lauren Petrullo   +3 more
wiley   +1 more source

Rat models of fetal alcohol spectrum disorders for studying the critical role of cerebellar damage: A scoping review

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
In rat models used to study the effects of early alcohol exposure on cerebellum function and structure during pregnancy and lactation, the following conclusions can be drawn: (1) Exposure to ethanol during the first and second‐trimester equivalent in humans affects biochemical pathways in the cerebellum, but produces fewer structural changes.
Fátima Nogales   +5 more
wiley   +1 more source

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