Results 31 to 40 of about 19,767 (298)
Molecular Medicine Reports, 2021 The present study aimed to analyze the effects and underlying mechanisms of microRNA (miR)-29-3p on the proliferation and secretory abilities of prolactinoma cells by targeting insulin-like growth factor (IGF)-1/β-catenin.
Jie Xia +5 more
semanticscholar +1 more source
Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]
, 2019 Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés +6 more
core +1 more source
Dopamine and prolactin in migraine: Mechanisms and potential therapeutic targets. [PDF]
J NeuroendocrinolProlactin and dopamine modulate migraine‐relevant trigeminal pathways. Hyperprolactinemia is associated with migraine‐like headache, and preclinical studies show that prolactin enhances trigeminal excitability, particularly in females. Dopamine inhibits prolactin release and may also directly suppress trigeminovascular activity via D2 receptors in the ...
Hjelholt AJ +3 more
europepmc +2 more sources
Case Report: Temozolomide Treatment of Refractory Prolactinoma Resistant to Dopamine Agonists
Frontiers in Endocrinology, 2021 Therapeutic agents for refractory prolactinomas that are resistant to dopamine agonists (DAs) are troublesome, and surgery often only removes a large part of the tumor without complete remission.
Hao Tang +5 more
semanticscholar +1 more source
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
, 2016 This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
The Turkish Journal of Pediatrics, 2022 Background. Hyperprolactinaemia refers to increased circulating prolactin and is divided into functional and pathological hyperprolactinaemia. Prolactinoma is the most common cause of severe hyperprolactinaemia. Prolactinomas are rare in children.
Tuğba Kontbay +6 more
doaj +1 more source
A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology [PDF]
, 2016 Pituitary adenomas are a common intracranial neoplasm, usually demonstrating a benign phenotype. They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and ...
Ansorge, Olaf +6 more
core +3 more sources
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
, 2001 Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta +7 more
core +1 more source
Cabergoline Treatment in Invasive Giant Prolactinoma
Clinical Medicine Insights: Case Reports, 2014 Patients with invasive giant prolactinoma suffer from a constellation of symptoms including headache, blurred vision, lethargy, and sexual dysfunction. Cabergoline, a potent dopamine agonist, is a known medication prescribed for the treatment of invasive
Sadeem Alsubaie, Mussa H. Almalki
doaj +1 more source
PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas
Frontiers in Endocrinology, 2022 BackgroundProlactinoma is the most common type of pituitary tumors, and its resultant tumor occupying and hormone disturbance greatly damage the health of patients.
Kejing Zhu +10 more
doaj +1 more source