Results 61 to 70 of about 10,512 (252)

Machine Learning for Outcome Prediction in First-Line Surgery of Prolactinomas. [PDF]

, 2022
Background First-line surgery for prolactinomas has gained increasing acceptance, but the indication still remains controversial. Thus, accurate prediction of unfavorable outcomes after upfront surgery in prolactinoma patients is critical for the ...
Andereggen, Lukas, Beck, Jürgen, Christ, Emanuel, Frey, Janine, Huber, Markus, Luedi, Markus M, Mariani, Luigi, Musahl, Christian, Schubert, Gerrit A, Tortora, Angelo   +9 more
core   +1 more source

Elevated Risk of Thyroid Malignancy in Biological Males Taking Estrogen Hormone Therapy

Otolaryngology–Head and Neck Surgery, Volume 172, Issue 4, Page 1192-1198, April 2025.
Abstract Objective The role of estrogen in developing thyroid malignancy is poorly understood. Epidemiological studies have shown exogenous estrogen is associated with increased risk in females. Still, no studies to date have investigated this association among biological males undergoing estrogen hormone therapy.
Andrew Meci, F. Jeffrey Lorenz, Neerav Goyal, David Goldenberg   +3 more
wiley   +1 more source

An uncommon cause of osteoporosis

Journal of Family Medicine and Primary Care, 2018
Osteoporosis in the younger age group is an important cause of morbidity. Prolactinoma is an uncommon but reversible cause of osteoporosis. The main mechanisms of osteoporosis in prolactinoma are reduced osteoblast activity and hypogonadism. A high index
Rohit Barnabas, Basavaraj Soora Gauda, Kripa Elizabeth Cherian, Nitin Kapoor, Hesarghatta Shyamasunder Asha, Thomas Vizhalil Paul   +5 more
doaj   +1 more source

A giant invasive macroprolactinoma with recurrent nasal bleeding as the first clinical presentation: case report and review of literature

BMC Endocrine Disorders, 2023
Background Giant prolactinoma (> 4 cm in dimension) is a rare disorder. Invasive macroprolactinoma has the potential to cause base of skull erosion and extend into the nasal cavity or even the sphenoid sinus.
Danting Li, Yan Wang, Huiwen Tan, Peiqiong Luo, Yerong Yu   +4 more
doaj   +1 more source

The PRolaCT studies — a study protocol for a combined randomised clinical trial and observational cohort study design in prolactinoma

Trials, 2021
Background First-line treatment for prolactinomas is a medical treatment with dopamine agonists (DAs), which effectively control hyperprolactinaemia in most patients, although post-withdrawal remission rates are approximately 34%.
Ingrid M. Zandbergen, Amir H. Zamanipoor Najafabadi, Iris C. M. Pelsma, M. Elske van den Akker-van Marle, Peter H. L. T. Bisschop, H. D. Jeroen Boogaarts, Arianne C. van Bon, Bakhtyar Burhani, Saskia le Cessie, Olaf M. Dekkers, Madeleine L. Drent, Richard A. Feelders, Johan P. de Graaf, J. Hoogmoed, Kitty K. Kapiteijn, Melanie M. van der Klauw, Willy-Anne C. M. Nieuwlaat, Alberto M. Pereira, Aline M. E. Stades, Annenienke C. van de Ven, Iris M. M. J. Wakelkamp, Wouter R. van Furth, Nienke R. Biermasz, on behalf of the Dutch Prolactinoma Study Group   +23 more
doaj   +1 more source

Relationship between prolactin plasma levels and white matter volume in women with multiple sclerosis [PDF]

, 2015
BACKGROUND: The role of prolactin (PRL) on tissue injury and repair mechanisms in multiple sclerosis (MS) remains unclear. The aim of this work was to investigate the relationship between PRL plasma levels and brain damage as measured by magnetic ...
Barletta, VALERIA TERESA, Contessa, Gian Marco, DE ANGELIS, Floriana, DE GIGLIO, Laura, Gurreri, F., Marinelli, Fabiana, Pantano, Patrizia, Piattella, MARIA CRISTINA, Pozzilli, Carlo, Prosperini, Luca, Tomassini, Valentina   +10 more
core   +4 more sources

Shortened Relative Leukocyte Telomere Length Is Associated With Polycystic Ovary Syndrome and Metabolic Traits

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 2, March 2025.
ABSTRACT Background Polycystic ovary syndrome (PCOS) is one of the commonest gyneco‐endocrine disorders amongst women of reproductive age. Whether PCOS and cardiometabolic traits in PCOS patients are associated with shortened telomere length (TL) or relative leukocyte telomere length (rLTL) remains unclear.
Raymond N.C. Chan, Chuiguo Huang, Noel Y. H. Ng, Henry C. H. Tam, Claudia H. T. Tam, Feifei Cheng, Kwun Kiu Wong, Mai Shi, Alex C. W. Ng, Atta Y. T. Tsang, Chi Chiu Wang, Lai Ping Cheung, Wing Hung Tam, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Juliana C. N. Chan, Cadmon K. P. Lim, Ronald C. W. Ma   +18 more
wiley   +1 more source

Management of resistant prolactinoma in infertile lady with successful maternal and perinatal outcome [PDF]

, 2017
Mrs. X of 28 years presented to the gynaecology department with primary infertility for 4 years, secondary amenorrhea for 6 months and galactorrhea for 3 months. She was investigated and diagnosed to have macroprolactinoma.
Manam, Gayathri, Pushpagiri, Niroopama
core   +2 more sources

EGFR and JAK2 were significant master gene biomarkers in invasive and noninvasive pituitary adenoma

Precision Medical Sciences, Volume 14, Issue 1, Page 4-14, March 2025.
(A) Visualization of the interactions between upregulated and downregulated genes in invasive and non‐invasive pituitary adenomas, highlighting the central role of EGFR and JAK2 as master gene biomarkers. (B) Expression density plots show the distribution of gene expression values after normalization, and volcano plots illustrate significant DEGs ...
Afsaneh Ghasemi, Zhila Fereidouni, Fahimeh Maleki‐Sheikhabadi, Fateme Shariati Far, Roya Dokoohaki, Hamid Zaferani Arani, Ahmad Bereimipour   +6 more
wiley   +1 more source

Peptide receptor radionuclide therapy with somatostatin analogs beyond gastroenteropancreatic neuroendocrine tumors

Journal of Neuroendocrinology, Volume 37, Issue 3, March 2025.
The thera(g)nostic approach with somatostatin analog‐based agents extends beyond gastroenteropancreatic neuroendocrine tumors. Understanding tumor biological mechanisms is essential for optimizing treatment strategies. Abstract First isolated by Brazeau et al. in 1972, somatostatin (SST) is a neuropeptide known for regulating various signaling pathways
Giulia Santo, Gianpaolo di Santo, Francesco Cicone, Irene Virgolini   +3 more
wiley   +1 more source