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To proliferate or not to proliferate [PDF]
Cardiovascular Research, 2010 This editorial refers to ‘Cardiomyocyte cell cycle control and growth estimation in vivo —an analysis based on cardiomyocyte nuclei’ by S. Walsh et al ., pp. 365–373, this issue. Cardiomyocytes in mammalian hearts undergo significant reduction in their cell proliferation capacity soon after birth, which is not disputed.
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Nature Communications, 2023 As one of the major components of plant cell walls, cellulose is crucial for plant growth and development. Cellulose is synthesized by cellulose synthase (CesA) complexes (CSCs), which are trafficked and delivered from the Golgi apparatus to the plasma ...
Lu Liu +7 more
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Postgraduate Medical Journal, 2002 Answers on p 251. A 63 year old man was referred by the general practitioner with a skin lesion on the right buttock which he had for three months. The …
Sapna Puppala +3 more
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BMC Cancer, 2019 Background S100A8 and S100A9, two heterodimer-forming members of the S100 family, aberrantly express in a variety of cancer types. However, little is known about the mechanism that regulates S100A8/S100A9 co-expression in cancer cells.
Yunguang Li +7 more
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Journal of Immunology, 1984 The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present investigation was to clarify whether the Ki-67 nuclear antigen is restricted in its expression to certain phases of the cell cycle.
J. Gerdes +5 more
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Non-Proliferation and Counter-Proliferation [PDF]
, 2018 European approaches to the proliferation of nuclear, biological, and chemical weapons—the so-called weapons of mass destruction (WMD)—have undergone a profound transformation during the last few decades. This chapter will trace the varying European policy responses to WMD proliferation over time and examine how European security doctrines have evolved ...
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A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth
Nature Communications, 2016 Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain ...
Joseph H.A. Vissers +3 more
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Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease
BMC Genomics, 2018 Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu +11 more
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Journal of Neuroscience, 1996 The hippocampus is one of the few areas of the rodent brain that continues to produce neurons postnatally. Neurogenesis reportedly persists in rats up to 11 months of age.
H. Georg +5 more
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Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer
eLife, 2022 Dendritic cells (DCs) play an important role in anti-tumor immunity by inducing T cell differentiation. Herein, we found that the DC mechanical sensor Piezo1 stimulated by mechanical stiffness or inflammatory signals directs the reciprocal ...
Yuexin Wang +10 more
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