Results 31 to 40 of about 3,582,903 (301)

KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function [PDF]

open access: yes, 2018
Estrogen receptor alpha (ER alpha) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas.
Abdel-Wahab, Omar   +13 more
core   +2 more sources

Meru co-ordinates spindle orientation with cell polarity and cell cycle progression

open access: yesThe EMBO Journal
Correct mitotic spindle alignment is essential for tissue architecture and plays an important role in cell fate specification through asymmetric cell division.
Melissa M McLellan   +5 more
doaj   +1 more source

Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming

open access: yeseLife, 2018
Understanding how cellular identity naturally interconverts with high efficiency and temporospatial precision is crucial for regenerative medicine. Here, we revealed a natural midgut-to-renal lineage conversion event during Drosophila metamorphosis and ...
Ke Xu   +4 more
doaj   +1 more source

Countering CBW Proliferation [PDF]

open access: yes, 2011
No description ...
McLeish, Caitriona, Smith, Mark
core   +1 more source

SCFSAP controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana [PDF]

open access: yes, 2016
Control of organ size by cell proliferation and growth is a fundamental process, but the mechanisms that determine the final size of organs are largely elusive in plants. We have previously revealed that the ubiquitin receptor DA1 regulates organ size by
Gonzalez Sanchez, Nathalie   +7 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

open access: yesNature Communications, 2017
Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly ...
Ning Huang   +7 more
doaj   +1 more source

α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization

open access: yeseLife, 2022
The centrosome composed of a pair of centrioles (mother and daughter) and pericentriolar material, and is mainly responsible for microtubule nucleation and anchorage in animal cells.
Dandan Ma   +9 more
doaj   +1 more source

No alternative to proliferation [PDF]

open access: yes, 2017
We reflect on the nature, role and limits of non-empirical theory assessment in fundamental physics, focusing in particular on quantum gravity. We argue for the usefulness and, to some extent, necessity of non-empirical theory assessment, but also ...
Oriti, Daniele
core   +1 more source

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