Results 51 to 60 of about 2,619,152 (303)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis

open access: yesTranslational Neurodegeneration, 2023
Background Persistent inflammatory response in the brain can lead to tissue damage and neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of inflammasomes, molecular platforms that drive inflammation through caspase-1 ...
Cristina de Dios   +7 more
doaj   +1 more source

The perinuclear theca protein Calicin helps shape the sperm head and maintain the nuclear structure in mice

open access: yesCell Reports, 2022
Summary: The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus; however, our understanding of the physiological roles of PT in sperm is very limited.
Xiao-Zhen Zhang   +4 more
doaj   +1 more source

No Alternative to Proliferation [PDF]

open access: yes, 2019
15 pages; contribution to the volume "Why trust a theory?", edited by: R. Dardashti, R. Dawid, K.
openaire   +3 more sources

Phytol and Peroxisome Proliferation [PDF]

open access: yesPediatric Research, 1986
Infantile Refsum's disease is characterized by high levels of phytanic acid and the absence of normal hepatic peroxisomes. We investigated the in vivo influence of phytol, a precursor of phytanic acid, on peroxisomes by both biochemical and morphological methods.
Van Den Branden, Christiane   +3 more
openaire   +3 more sources

CD29 of human umbilical cord mesenchymal stem cells is required for expansion of CD34(+) cells

open access: yes, 2014
ObjectivesHuman umbilical cord mesenchymal stem cells (hUCMSCs) play a critical role in expanding haematopoietic stem cells (HSCs) by providing the essential microenvironment for haematopoiesis.
Yang, Y.   +4 more
core   +1 more source

Natriuretic peptide receptors on rat thymocytes: Inhibition of proliferation by atrial natriuretic peptide. [PDF]

open access: yes, 1996
Because the thymus expresses the natriuretic peptides (NP) as well as their respective receptors, an involvement of NP in the physiology of this organ has been suggested.
Schmidt, Karin-Nicole   +3 more
core   +2 more sources

CircADAMTS16 Inhibits Differentiation and Promotes Proliferation of Bovine Adipocytes by Targeting miR-10167-3p

open access: yes, 2023
Circular RNAs (CircRNAs) are covalently closed-loop non-coding RNA (ncRNA) molecules present in eukaryotes. Numerous studies have demonstrated that circRNAs are important regulators of bovine fat deposition, but their precise mechanisms remain unclear ...
Yun Ma   +6 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

cdiener/proliferation: proliferation v0.3.4

open access: yes, 2016
<p>This is archived repository of version 0.3.4 of the proliferation pipeline. It includes instructions and additional files to reproduce the entire analysis.</p> <p>For usage instruction please see the README.md file.</p ...
Christian Diener   +3 more
core   +1 more source

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