Results 21 to 30 of about 2,929,257 (346)

TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

open access: yesNature Communications, 2018
Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Guoliang Lyu   +10 more
doaj   +1 more source

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

open access: yesCells, 2020
The vitamin K-dependent factors protein S (PROS1) and growth-arrest-specific gene 6 (GAS6) and their tyrosine kinase receptors TYRO3, AXL, and MERTK, the TAM subfamily of receptor tyrosine kinases (RTK), are key regulators of inflammation and vascular ...
Anna Tutusaus   +5 more
doaj   +1 more source

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

open access: yesCancers, 2017
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar   +1 more source

A Prize for Proliferation [PDF]

open access: yesCell, 2001
As an avid reader of the Economist, I was disappointed by their suggestion that the Nobel committee had “blown” it in giving this year's prize for medicine and physiology to the discoverers of Cdks and not to those who had just sequenced the human genome.
openaire   +3 more sources

Global proliferation of cephalopods [PDF]

open access: yesCurrent Biology, 2016
Human activities have substantially changed the world's oceans in recent decades, altering marine food webs, habitats and biogeochemical processes [1]. Cephalopods (squid, cuttlefish and octopuses) have a unique set of biological traits, including rapid growth, short lifespans and strong life-history plasticity, allowing them to adapt quickly to ...
Doubleday, Zoë A.   +10 more
openaire   +7 more sources

A Novel Acyl-AcpM-Binding Protein Confers Intrinsic Sensitivity to Fatty Acid Synthase Type II Inhibitors in Mycobacterium smegmatis

open access: yesFrontiers in Microbiology, 2022
The fatty acid synthase type II (FAS-II) multienzyme system is the main target of drugs to inhibit mycolic acid synthesis in mycobacterium. Meromycolate extension acyl carrier protein (AcpM) serves as the carrier of fatty acyl chain shuttling among the ...
Mengmiao Li   +7 more
doaj   +1 more source

Retinopathy of prematurity: indicators of cellular immunity in patients with various stages of the disease

open access: yesРоссийский офтальмологический журнал, 2019
Purpose: to study the role of cellular immunity in the development of retinopathy of prematurity (ROP).Material and methods. 87 children were tested, including 60 with III — V stage ROP and posterior aggressive retinopathy that had gestational age from ...
L. M. Balashova   +6 more
doaj   +1 more source

α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization

open access: yeseLife, 2022
The centrosome composed of a pair of centrioles (mother and daughter) and pericentriolar material, and is mainly responsible for microtubule nucleation and anchorage in animal cells.
Dandan Ma   +9 more
doaj   +1 more source

Transition from inflammation to proliferation: a critical step during wound healing

open access: yesCellular and Molecular Life Sciences, 2016
The ability to rapidly restore the integrity of a broken skin barrier is critical and is the ultimate goal of therapies for hard-to-heal-ulcers. Unfortunately effective treatments to enhance healing and reduce scarring are still lacking.
N. Landén, Dongqing Li, M. Ståhle
semanticscholar   +1 more source

Compensatory proliferation and apoptosis-induced proliferation: a need for clarification [PDF]

open access: yesCell Death & Differentiation, 2012
Peer ...
Mollereau, Bertrand   +7 more
openaire   +6 more sources

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