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Sphingomyelinases and Liver Diseases
Sphingolipids (SLs) are critical components of membrane bilayers that play a crucial role in their physico-chemical properties. Ceramide is the prototype and most studied SL due to its role as a second messenger in the regulation of multiple signaling ...
Naroa Insausti-Urkia+3 more
doaj +1 more source
A lipid-structured mathematical model of atherosclerosis with macrophage proliferation [PDF]
We extend the lipid-structured model for atherosclerotic plaque development of Ford et al. (2019) to account for macrophage proliferation. Proliferation is modelled as a non-local decrease in the lipid structural variable that is similar to the treatment of cell division in size-structured models (e.g. Efendiev et al. (2018)).
arxiv
Skin Cell Proliferation Stimulated by Microneedles [PDF]
A classical wound may be defined as a disruption of tissue integrity. Wounds, caused by trauma from accidents or surgery, that close via secondary intention rely on the biological phases of healing, i.e., hemostasis, inflammation, proliferation, and ...
Kloth, Luther C., Liebl, Horst
core +2 more sources
Director`s series on proliferation [PDF]
This is an occasional publication of essays on the topics of nuclear, chemical, biological, and missile proliferation. The views represented are those of the author`s. Essay topics include: Nuclear Proliferation: Myth and Reality; Problems of Enforcing Compliance with Arms Control Agreements; The Unreliability of the Russian Officer Corps: Reluctant ...
Bailey, K. C., Price, M. E.
openaire +11 more sources
The genetic transformation of target cells is a key tool in modern biological research, as well as in many gene therapy and biotechnology applications. Here we describe a new method for delivery of DNA into several industrially important species of yeast,
Yevhen Filyak+7 more
doaj +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Applications of hydrodynamic models for modeling drifting jellyfish blooms around the Maltese Islands [PDF]
Within the ambit of the MED-JELLYRISK project, the IOI-Malta Operational Centre is coordinating the development of a jellyfish dispersion model capable of generating both a hindcast and a forecast (extending up to a maximum of 4 days following day of ...
Deidun, Alan+1 more
core
Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling [PDF]
Neuroinflammation is characterized by activation of microglial cells, followed by production of nitric oxide (NO), which may have different outcomes on neurogenesis, favoring or inhibiting this process.
Alvarez-Buylla+85 more
core +2 more sources
To be or not to be a proliferation marker? [PDF]
Whether it is nobler in the mind to suffer the slings and arrows of outrageous proliferation, or to take arms against stroma, and favor metastasis… This pastiche of Hamlet's famous monologue illustrates recent reports on the paradoxical functions of well-established proliferation markers such as c-Myc or cyclin A2 that have revealed their ambiguous ...
openaire +4 more sources
Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III
Background The relationship between transcription and the 3D chromatin structure is debated. Multiple studies have shown that transcription affects global Cohesin binding and 3D genome structures.
Yongpeng Jiang+12 more
doaj +1 more source