Results 131 to 140 of about 12,701 (190)
Chemical Ligation of Backbone N‐hydroxylated Peptides
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio +1 more
wiley +1 more source
Abstract Biostimulants are increasingly used in agriculture to promote plant growth, improve stress tolerance, and support sustainable farming practices. One common method of production is chemical hydrolysis of protein‐rich waste, such as tannery by‐products, offering an economical and eco‐friendly alternative to conventional raw materials.
Karel Kolomazník +3 more
wiley +1 more source
Polymeric and molecular amines embedded in hygroscopic matrices to facilitate CO2 transport for CO2/H2 separation. Abstract This work dealt with composite membranes comprising of polyvinylamine (PVAm) and triethylenetetramine (TETA) embedded in poly(vinyl alcohol) (PVA) for CO2/H2 separation via facilitated transport of CO2, where polymeric and ...
Steve Yijie Hu, Kean Wang, Xianshe Feng
wiley +1 more source
Expert Consensus on Real‐World Use of Trofinetide for Rett Syndrome Using a Modified Delphi Method
ABSTRACT Objective Trofinetide is the first approved treatment for Rett syndrome (RTT) in the United States and Canada. Trofinetide improved the core symptoms of RTT in clinical trials, and real‐world evidence supports the findings of clinical trials.
Erin O'Connor Prange +4 more
wiley +1 more source
How Amino Acids Intercalate in CaFe Layered Double Hydroxides: A Combined RIXS and NEXAFS Study
Intercalation of amino acids in layered double hydroxides offers a road to functional (bio)catalysts. With resonant soft x‐ray spectroscopy we probe the electronic structure of these systems and observe activation and passivation of electronic states as well as bond formation between the amino acid and the LDH upon intercalation.
R. Büchner +4 more
wiley +1 more source
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka +12 more
wiley +1 more source
An efficient, metal‐free electrochemical three‐component reaction of cinnamic acids, SO2, and amines to access (E)‐β‐styryl sulfonamides is reported. Utilizing graphite electrodes and SO2 stock solutions, this decarboxylative protocol proceeds under mild conditions with high regio‐ and stereoselectivity.
Po‐Chung Chien +2 more
wiley +1 more source
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Efficient Enantiomeric Selectivity Separation Via Homochiral Graphene Oxide Membrane
A new type of chiral graphene oxide (GO) membrane is proposed that exhibits a separation factor of up to 20.1 as well as a preferential enantiomer flux of 4.5 mmol m−2 h−1. Moreover, the only first FPLC‐compatible column has been further developed via stacking these chiral GO membranes.
Junbo Wang +10 more
wiley +1 more source

