Results 161 to 170 of about 12,701 (190)
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Journal of the American Chemical Society, 1977
The present study concerns the energies of the conformations of proline. We present results of an improved molecular mechanics calculation for ring conformations of Ac-Pro-OCH/sub 3/ and for the s-cis and s-trans conformations. Internal coordinates including all torsions have been calculated from crystal coordinates for more than 40 x-ray ...
D F, De Tar, N P, Luthra
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The present study concerns the energies of the conformations of proline. We present results of an improved molecular mechanics calculation for ring conformations of Ac-Pro-OCH/sub 3/ and for the s-cis and s-trans conformations. Internal coordinates including all torsions have been calculated from crystal coordinates for more than 40 x-ray ...
D F, De Tar, N P, Luthra
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Proline-Specific Endopeptidases
Russian Journal of Bioorganic Chemistry, 2003Prolyl endopeptidases, or post-proline-cleaving enzymes, are the specific endopeptidases that hydrolyze peptide substrates at the carbonyl of the internal Pro residue. All the currently known prolyl endopeptidases from animals, microorganisms, fungi, and plants as well as the post-proline-cleaving enzymes that do not exhibit the strict specificity to ...
D V, Besedin, G N, Rudenskaia
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EcoSal Plus, 2007
Proline was among the last biosynthetic precursors to have its biosynthetic pathway unraveled. This review recapitulates the findings on the biosynthesis and transport of proline. Glutamyl kinase (GK) catalyzes the ATP-dependent phosphorylation of L-glutamic acid.
Laszlo N, Csonka, Thomas, Leisinger
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Proline was among the last biosynthetic precursors to have its biosynthetic pathway unraveled. This review recapitulates the findings on the biosynthesis and transport of proline. Glutamyl kinase (GK) catalyzes the ATP-dependent phosphorylation of L-glutamic acid.
Laszlo N, Csonka, Thomas, Leisinger
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Supported proline and proline-derivatives as recyclable organocatalysts
Chemical Society Reviews, 2008In the last eight years, L-proline and L-proline derivatives, such as substituted prolinamides or pyrrolidines, have been successfully used as organocatalysts in several reactions. In this critical review we summarize the immobilization procedures of such organocatalysts highlighting their application, recoverability and reusability (86 references).
GRUTTADAURIA, Michelangelo +2 more
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Fasciolicidal potential of proline analogues and proline biosynthesis inhibitors
International Journal for Parasitology, 1982Abstract Sheers Marion , Campbell Anne J. , Beames D. J. , Edwards S. R. , Moore R. J. and Montague P. E. 1982. Fasciolicidal potential of proline analogues and proline biosynthesis inhibitors. International Journal for Parasitology 12 : 47–52.
M, Sheers +5 more
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Mechanism-based inhibition of proline dehydrogenase by proline analogues
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1993The inactivation of proline dehydrogenase by several L-Pro analogues was investigated with the aim to block the essential metabolic pathway of tsetse flies allowing the degradation of L-Pro to L-Glu. In vitro studies on rat liver mitochondria showed that only 4-methylene-L-proline was able to inactivate proline dehydrogenase.
D, Tritsch, H, Mawlawi, J F, Biellmann
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Proline metabolism in cartilage: The importance of proline biosynthesis
Metabolism, 1978Abstract Mammalian cells have the capacity to synthesize proline from ornithine or glutamic acid, although preformed proline usually is available from extracellular sources. We have measured the rate of proline formation from ornithine in the presence of physiologic concentrations of proline. In rat xiphoid cartilage organ cultures with ornithine and
R J, Smith, J M, Phang
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