Results 211 to 220 of about 583,561 (341)

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

Advanced Science, EarlyView.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang, Bohao Liu, Xingzhuo Zhu, Deqian Qiao, Sizhe Chen, Xiaoyan Zeng, Qingqing Yang, Zihuan Wei, Yinjuan Huang, Jizhao Wang, Guangjian Zhang, Qiuyu Gong   +11 more
wiley   +1 more source

Shifts in amino acids profile in chronic pancreatitis. [PDF]

PLoS One
Malvik M, Kilk K, Müller R, Salupere R, Zilmer M, Lember M.   +5 more
europepmc   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

Force writes memory: proline isomerization as a molecular memory switch. [PDF]

Biochem Soc Trans
Popa I, Berkovich R.
europepmc   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

A proof-of-concept study: investigating the impact of COMT genotype and proline on negative symptoms in Alzheimer's disease. [PDF]

BJPsych Open
Clelland JD, Cure HW, Canizares AM, Anderson JH, Rawal B, Wong SA, Kerner N, Huey ED, Honig LS, Devanand DP, Clelland CL.   +10 more
europepmc   +1 more source

Studies of proton conducting polymer electrolyte based on PVA, amino acid proline and NH4SCN

, 2019
R. Hemalatha, M. Alagar, S. Selvasekarapandian, B. Sundaresan, V. Moniha   +4 more
openalex   +1 more source

Rates of collagen synthesis in lung, skin and muscle obtained in vivo by a simplified method using [3H]proline [PDF]

, 1983

openalex   +1 more source

A Scalable Method for Cavity‐Enhanced Solid‐State Quantum Sensors

Advanced Science, EarlyView.
Photoluminescent color centres in diamond and hexagon boron nitride are powerful nanoscale solid‐state quantum sensors. Methods for integrating them into macroscopic structures that improve their sensitivity are highly sought after. This study demonstrates a low‐cost and scalable method for the fabrication of quantum sensor‐doped thin‐film cavities ...
Daniel J. Tibben, Roy Styles, David A. Broadway, Jean‐Philippe Tetienne, Daniel E. Gómez, Philipp Reineck   +5 more
wiley   +1 more source

Acclimatization of Cicer arietinum L. plants to salinity: examining the relief role of autochthonous mycorrhiza and exogenous proline. [PDF]

BMC Plant Biol
Abdelhameed RE, Metwally RA.
europepmc   +1 more source