Results 71 to 80 of about 329,298 (293)

Exploring plant-derived matrices for proline encapsulation to enhance proline-mediated heat stress tolerance

open access: yesPlant Stress
Proline plays a central role in plant adaptation to abiotic stress, but its exogenous application at high concentrations may disrupt proline metabolism and promote oxidative damage. This study evaluated whether controlled foliar delivery of proline using
Vanessa A. Avendaño   +3 more
doaj   +1 more source

Formation of bioinorganic complexes by the corrosive adsorption of (S)-proline on Ni/Au(111) [PDF]

open access: yes, 2015
R.T.S.G. and J.G. acknowledge the Engineering and Physical Sciences Research Council (EPSRC, UK) for the award of a PhD studentship. The research leading to these results has received funding from the European Community’s Seventh Framework Programme (FP7/
Baddeley, Christopher John   +12 more
core   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

open access: yesAdvanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker   +7 more
wiley   +1 more source

Proline puckering parameters for collagen structure simulations

open access: yesAIP Advances, 2015
Collagen is made of triple helices rich in proline residues, and hence is influenced by the conformational motions of prolines. Because the backbone motions of prolines are restricted by the helical structures, the only side chain motion—proline ...
Di Wu
doaj   +1 more source

Disruption of fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinase [PDF]

open access: yes, 2013
Fyn-deficient mice display increased AMP-activated Protein Kinase (AMPK) activity as a result of Fyn-dependent regulation of Liver Kinase B1 (LKB1) in skeletal muscle.
Bastie, Claire C.   +8 more
core   +1 more source

Universal Gripper for Industrial Manipulation With Enhanced Rigid Mechanics and Self‐Adaptable Fingers

open access: yesAdvanced Robotics Research, EarlyView.
An enhanced universal gripper combining rigid mechanics with self‐adaptable fingers is presented for industrial automation. The novel six‐bar linkage with integrated compliant pad eliminates mechanical interference while enabling passive shape adaptation.
Muhammad Usman Khalid   +7 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Proline-Mediated Transition Metal-Free Access to 1H‑Indazolones from 2‑Halobenzohydrazides

open access: yes, 2016
Transition metal-free access to 1H-indazolones 1 has been achieved on the basis of base-mediated intramolecular C–N bond formation. Reactions of 2-halobenzohydrazides 2 with potassium tert-butoxide in the presence of catalytic proline provided ...
Miho Tsujii (2879000)   +2 more
core   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Характеристика трансгенних рослин соняшника (Helianthus annuus L.) з дволанцюговим РНК супрессором гена проліндегідрогенази

open access: yesФактори експериментальної еволюції організмів, 2016
Aim. The obtaining of osmotolerant form of sunflower (Helianthus annuus L.) by siRNA-technology. Methods. Agrobacterium-mediated transformation using LBA4404 harboring pBi2E with double-stranded RNA-suppressor, produced based on the ProDH1 gene of ...
А. Г. Комісаренко   +3 more
doaj  

Home - About - Disclaimer - Privacy