Results 111 to 120 of about 29,796 (189)

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2838-2868, August 2026.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source

Melatonin seed priming: A climate‐smart, green strategy to enhance abiotic stress tolerance in plants

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2942-2975, August 2026.
This review synthesizes how melatonin seed priming preconditions seeds to enhance tolerance against diverse abiotic stresses. It highlights the underlying mechanisms and proposes an integrative roadmap of advanced molecular and breeding tools to design next‐generation, stress‐smart plants.
Ali Raza, Yiran Li, Chunli Guo, Erna Karalija, Evgenios Agathokleous, Meng Jiang, Jie Zhou, Vasileios Fotopoulos, Zhangli Hu   +8 more
wiley   +1 more source

Proline Oxidase, a Proapoptotic Gene, Is Induced by Troglitazone [PDF]

Journal of Biological Chemistry, 2006
Jui Pandhare, Sandra K. Cooper, James M. Phang   +2 more
openaire   +1 more source

Strigolactone‐mediated architecture regulation and stress resilience: Insights and innovations for crop breeding

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2548-2576, August 2026.
This review summarizes the discovery, biosynthesis, and transport of strigolactone, and the D14‐D3/MAX2‐D53/SMXLs signaling module. It highlights diverse roles of strigolactone in plant architecture, stress responses, and crop breeding, including species‐specific functions, hormonal crosstalk, and agricultural applications.
Qingliang Hu, Jiayang Li, Bing Wang
wiley   +1 more source

14‐3‐3 proteins: Central hubs in plant development and stress adaptation

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 3107-3132, August 2026.
This review highlights recent advances elucidating the important roles of 14‐3‐3 proteins in regulating phytohormone networks, biotic and abiotic stress tolerance, growth‐defense trade‐offs, and evolutionary adaptations. Furthermore, it provides a forward‐looking perspective on 14‐3‐3 biology and the development of climate‐resilient smart crops under ...
Jiale Yuan, Qizhang Wang, Jing Cao, Furong Wang, Hua Zhou, Jigang Li, Fang Lin   +6 more
wiley   +1 more source

Plant G proteins: Versatile signaling hubs for synergistic improvement of agronomic traits

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 3133-3152, August 2026.
This review highlights the roles of G‐protein signaling in crop yield and quality, as well as abiotic and biotic stress responses. It also discusses the feasibility of breaking the trade‐off between plant growth and stress tolerance via dissecting G‐protein regulatory pathways, gene editing, mining natural elite variants, and AI‐assisted breeding ...
Haoran Li, Zhilong Zhang, Fangyuan Liu, Haonan Wang, Zebiao He, Sanyuan Tang, Xiaojing Dong, Peng Xie   +7 more
wiley   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, Volume 251, Issue 3, Page 975-995, August 2026.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy. [PDF]

J Biol Chem, 2015
Pandhare J, Dash S, Jones B, Villalta F, Dash C.   +4 more
europepmc   +1 more source