Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids [PDF]
This study investigated the reactivity of sarcosine oxidase (Sox) toward minor substrates through kinetic and structural analyses, along with mutational engineering to elucidate their reaction mechanisms. Sarcosine oxidase from Bacillus sp.
Yuqi Zhang +5 more
doaj +2 more sources
Proline reduces brain cytochrome c oxidase: prevention by antioxidants
In the present study, we initially investigated the in vivo (acute and chronic) and in vitro effects of proline on cytochrome c oxidase (complex IV) activity in rat cerebral cortex to test the hypothesis that proline might alter energy metabolism and ...
Daniela Delwing +2 more
exaly +1 more source
Effects of NaCl and Proline on Polyphenol Oxidase Activity in Bean Seedlings
In this work, the effects of NaCl (0, 50, 100, and 150 mM), proline (0, 5 and 10 mM) and NaCl + proline in combinations on activity of polyphenol oxidase (PPO; E.C.
Demir, Yavuz +4 more
core +5 more sources
Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy [PDF]
Thi Yen Ly Huynh +2 more
exaly +2 more sources
A novel plausible mechanism of NSAIDs-induced apoptosis in cancer cells: the implication of proline oxidase and peroxisome proliferator-activated receptor [PDF]
Adam Kazberuk +2 more
exaly +2 more sources
Polyethylene glycol and proline synergistically improve salinity tolerance via physiological and biochemical reprogramming in mango [PDF]
Background Mango (Mangifera indica L.) is a globally important fruit crop, but its sensitivity to salt stress poses a serious threat to its sustainable cultivation.
Mohamed El Kheshin, Ibrahim Hmmam
doaj +2 more sources
Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle [PDF]
Hepatitis C virus (HCV) is an oncogenic virus that causes chronic liver disease in more than 80% of patients. During the last decade, efficient direct-acting antivirals were introduced into clinical practice.
Natalia F. Zakirova +17 more
doaj +2 more sources
Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells. [PDF]
Proline degradation by proline dehydrogenase/proline oxidase (PRODH/POX) contributes to apoptosis or autophagy. The identification of specific pathway of apoptosis/survival regulation is the aim of this study. We generated knocked-down PRODH/POX MCF-7 breast cancer cells (MCF-7shPRODH/POX). PRODH/POX silencing did not affect cell viability. However, it
Zareba I +4 more
europepmc +4 more sources
Physiological and biochemical characteristics of some therophyllous species of the Ficus genus in water stress conditions [PDF]
The relevance of the search for physiological and biochemical parameters associated with the implementation of plant adaptation mechanisms to the combined action of high temperatures and water stress is dictated by frequent summer droughts in southern ...
Grebennikova Oksana, Pilkeviсh Ruslana
doaj +1 more source
Effect of drought stress on biochemical contents and proline metabolizing enzymes of Pennisetum glaucum L. [PDF]
Drought stress is one of the major environmental problem affecting agricultural production in arid and semi-arid regions of the world. In present study, the effect of drought stress on Pennisetum glaucum L. (Pearl millet) plants was studied.
S. Suganthi +3 more
doaj +3 more sources

